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NeurIPS 2025

A Data-Driven Prism: Multi-View Source Separation with Diffusion Model Priors

Conference Paper Main Conference Track Artificial Intelligence ยท Machine Learning

Abstract

In the natural sciences, a common challenge is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual neurons from overlapping signals, and separating seismic events from the ambient background. Traditional analyses often rely on simplified source models that fail to accurately reproduce the data. Recent advances have shown that diffusion models can directly learn complex prior distributions from noisy, incomplete data. In this work, we show that diffusion models can solve the source separation problem without explicit assumptions about the source. Our method relies only on multiple views, or the property that different sets of observations contain different linear transformations of the unknown sources. We show that our method succeeds even when no source is individually observed and the observations are noisy, incomplete, and vary in resolution. The learned diffusion models enable us to sample from the source priors, evaluate the probability of candidate sources, and draw from the joint posterior of our sources given an observation. We demonstrate the effectiveness of our method on a range of synthetic problems as well as real-world galaxy observations.

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Context

Venue
Annual Conference on Neural Information Processing Systems
Archive span
1987-2025
Indexed papers
30776
Paper id
955174782984208965