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Zongyi Chen

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AAAI Conference 2026 Conference Paper

CRAF: A Clinical Reasoning-Adaptive Framework via Reinforcement Learning for Similar Case Retrieval

Jie Lin
Lei Jiang
Zongyi Chen
Liansheng Wang

With the advancement of information retrieval (IR) technologies toward deep semantic understanding, reasoning-based methods—featuring explicit chain-of-thought generation—have demonstrated significant advantages in multi-hop and causal reasoning tasks. However, in complex clinical case retrieval scenarios, implicit reasoning cues within clinical data often hinder current models from effectively capturing deep semantic associations between queries and cases. Query rewriting and expansion techniques based on reasoning offer a promising solution to this challenge by uncovering and completing the latent clinical intent behind user queries, thereby enhancing semantic coverage and reasoning sensitivity. In this paper, we propose CRAF, a clinically adaptive reasoning framework tailored for similar case retrieval. Our method generates clinical reasoning paths and incorporates a fine-grained semantic reward mechanism, enabling efficient query rewriting through reinforcement learning. Experimental results on the PMC-Patients benchmark demonstrate that CRAF consistently delivers robust improvements across multiple retrieval tasks, achieving reasoning performance comparable to that of commercial models.

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AAAI Conference 2022 Conference Paper

Explainable Survival Analysis with Convolution-Involved Vision Transformer

Yifan Shen
Li Liu
Zhihao Tang
Zongyi Chen
Guixiang Ma
Jiyan Dong
Xi Zhang
Lin Yang

Image-based survival prediction models can facilitate doctors in diagnosing and treating cancer patients. With the advance of digital pathology technologies, the big whole slide images (WSIs) provide increased resolution and more details for diagnosis. However, the gigabytesize or even terabyte-size WSIs would make most models computationally infeasible. To this end, instead of using the complete WSIs, most of the existing models only use a pre-selected subset of key patches or patch clusters as input, which might discard some important morphology information. In this work, we propose a novel survival analysis model to fully utilize the complete WSI information. We show that the use of a Vision Transformer (ViT) backbone, together with convolution operations involved in it, is an effective approach to improve the prediction performance. Additionally, we present a post-hoc explainable method to identify the most salient patches and distinct morphology features, making the model more faithful and the results easier to comprehend by human users. Evaluations on two large cancer datasets show that our proposed model is more effective and has better interpretability for survival prediction. We would make the code publicly available upon acceptance.

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