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Zhongyi Han

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7 papers

1 author row

AAAI Conference 2026 Conference Paper

Retriever Encoder Selection Matters for In-Context Learning-based Medical Segmentation

Fan Wang
Zhongyi Han
Yongshun Gong
Yilong Yin

In-context learning-based medical segmentation (ICLM) enables foundation models to generalize to unseen cases without retraining. To enhance performance on test queries, existing methods typically follow a two-stage process: (1) using a retrieval encoder (RE) to map both queries and training samples into a shared feature space, and (2) retrieving and utilizing the top-k most similar training samples. While current methods fix the RE and focus on optimizing stage (2), we show that the choice of RE in stage (1) alone can account for over 70% of the performance variation, highlighting RE selection as a critical yet often overlooked factor in ICLM. In this paper, we conduct an analysis of the RE selection and make two main findings: (1) dynamically selecting the RE for each query outperforms selecting a fixed RE for the entire task; and (2) feature-space heuristics (e.g., intra-class compactness and inter-class separability) fail to predict RE quality. To this end, we propose the instance-adaptive retrieval encoder selection (IRES) method that can select the optimal RE for each query based on output predictions. IRES is based on the intuition that a good RE retrieves relevant demonstrations, helping the ICL model generate more accurate and stable segmentation masks. Thus, we introduce the shape stability score (S³), which evaluates the morphological stability of predicted masks under iterative erosion. Experiments show S³ correlates strongly with true RE quality (Pearson > 0.8), serving as a reliable selection proxy. To reduce S³’s per-query cost, we propose parallel prediction with reciprocal neighbor reuse (P2R), which accelerates inference by parallelizing encoding and reusing encoder selections across reciprocal neighbors, avoiding redundant computation. Built on S³ and P2R, IRES improves ICLM performance across FUNDUS, Brain MRI, and Chest X-ray datasets, with up to 10.6% gain on fundus segmentation.

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NeurIPS Conference 2025 Conference Paper

From Pretraining to Pathology: How Noise Leads to Catastrophic Inheritance in Medical Models

Hao Sun
Zhongyi Han
Hao Chen
Jindong Wang
Xin Gao
Yilong Yin

Foundation models pretrained on web-scale data drive contemporary transfer learning in vision, language, and multimodal tasks. Recent work shows that mild label noise in these corpora may lift in-distribution accuracy yet sharply reduce out-of-distribution generalization, an effect known as catastrophic inheritance. Medical data is especially sensitive because annotations are scarce, domain shifts are large, and pretraining sources are noisy. We present the first systematic analysis of catastrophic inheritance in medical models. Controlled label-corruption experiments expose a clear structural collapse: as noise rises, the skewness and kurtosis of feature and logit distributions decline, signaling a flattened representation space and diminished discriminative detail. These higher-order statistics form a compact, interpretable marker of degradation in fine-grained tasks such as histopathology. Guided by this finding, we introduce a fine-tuning objective that restores skewness and kurtosis through two scalar regularizers added to the task loss. The method leaves the backbone unchanged and incurs negligible overhead. Tests on PLIP models trained with Twitter pathology images, as well as other large-scale vision and language backbones, show consistent gains in robustness and cross-domain accuracy under varied noise levels.

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AAAI Conference 2024 Conference Paper

Exploring Channel-Aware Typical Features for Out-of-Distribution Detection

Rundong He
Yue Yuan
Zhongyi Han
Fan Wang
Wan Su
Yilong Yin
Tongliang Liu
Yongshun Gong

Detecting out-of-distribution (OOD) data is essential to ensure the reliability of machine learning models when deployed in real-world scenarios. Different from most previous test-time OOD detection methods that focus on designing OOD scores, we delve into the challenges in OOD detection from the perspective of typicality and regard the feature’s high-probability region as the feature’s typical set. However, the existing typical-feature-based OOD detection method implies an assumption: the proportion of typical feature sets for each channel is fixed. According to our experimental analysis, each channel contributes differently to OOD detection. Adopting a fixed proportion for all channels results in several channels losing too many typical features or incorporating too many abnormal features, resulting in low performance. Therefore, exploring the channel-aware typical features is crucial to better-separating ID and OOD data. Driven by this insight, we propose expLoring channel-Aware tyPical featureS (LAPS). Firstly, LAPS obtains the channel-aware typical set by calibrating the channel-level typical set with the global typical set from the mean and standard deviation. Then, LAPS rectifies the features into channel-aware typical sets to obtain channel-aware typical features. Finally, LAPS leverages the channel-aware typical features to calculate the energy score for OOD detection. Theoretical and visual analyses verify that LAPS achieves a better bias-variance trade-off. Experiments verify the effectiveness and generalization of LAPS under different architectures and OOD scores.

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AAAI Conference 2023 Conference Paper

Discriminability and Transferability Estimation: A Bayesian Source Importance Estimation Approach for Multi-Source-Free Domain Adaptation

Zhongyi Han
Zhiyan Zhang
Fan Wang
Rundong He
Wan Su
Xiaoming Xi
Yilong Yin

Source free domain adaptation (SFDA) transfers a single-source model to the unlabeled target domain without accessing the source data. With the intelligence development of various fields, a zoo of source models is more commonly available, arising in a new setting called multi-source-free domain adaptation (MSFDA). We find that the critical inborn challenge of MSFDA is how to estimate the importance (contribution) of each source model. In this paper, we shed new Bayesian light on the fact that the posterior probability of source importance connects to discriminability and transferability. We propose Discriminability And Transferability Estimation (DATE), a universal solution for source importance estimation. Specifically, a proxy discriminability perception module equips with habitat uncertainty and density to evaluate each sample's surrounding environment. A source-similarity transferability perception module quantifies the data distribution similarity and encourages the transferability to be reasonably distributed with a domain diversity loss. Extensive experiments show that DATE can precisely and objectively estimate the source importance and outperform prior arts by non-trivial margins. Moreover, experiments demonstrate that DATE can take the most popular SFDA networks as backbones and make them become advanced MSFDA solutions.

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NeurIPS Conference 2023 Conference Paper

Subclass-Dominant Label Noise: A Counterexample for the Success of Early Stopping

Yingbin Bai
Zhongyi Han
Erkun Yang
Jun Yu
Bo Han
Dadong Wang
Tongliang Liu

In this paper, we empirically investigate a previously overlooked and widespread type of label noise, subclass-dominant label noise (SDN). Our findings reveal that, during the early stages of training, deep neural networks can rapidly memorize mislabeled examples in SDN. This phenomenon poses challenges in effectively selecting confident examples using conventional early stopping techniques. To address this issue, we delve into the properties of SDN and observe that long-trained representations are superior at capturing the high-level semantics of mislabeled examples, leading to a clustering effect where similar examples are grouped together. Based on this observation, we propose a novel method called NoiseCluster that leverages the geometric structures of long-trained representations to identify and correct SDN. Our experiments demonstrate that NoiseCluster outperforms state-of-the-art baselines on both synthetic and real-world datasets, highlighting the importance of addressing SDN in learning with noisy labels. The code is available at https: //github. com/tmllab/2023 NeurIPS SDN.

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AAAI Conference 2022 Conference Paper

Not All Parameters Should Be Treated Equally: Deep Safe Semi-supervised Learning under Class Distribution Mismatch

Rundong He
Zhongyi Han
Yang Yang
Yilong Yin

Deep semi-supervised learning (SSL) aims to utilize a sizeable unlabeled set to train deep networks, thereby reducing the dependence on labeled instances. However, the unlabeled set often carries unseen classes that cause the deep SSL algorithm to lose generalization. Previous works focus on the data level that they attempt to remove unseen class data or assign lower weight to them but could not eliminate their adverse effects on the SSL algorithm. Rather than focusing on the data level, this paper turns attention to the model parameter level. We find that only partial parameters are essential for seen-class classification, termed safe parameters. In contrast, the other parameters tend to fit irrelevant data, termed harmful parameters. Driven by this insight, we propose Safe Parameter Learning (SPL) to discover safe parameters and make the harmful parameters inactive, such that we can mitigate the adverse effects caused by unseen-class data. Specifically, we firstly design an effective strategy to divide all parameters in the pre-trained SSL model into safe and harmful ones. Then, we introduce a bi-level optimization strategy to update the safe parameters and kill the harmful parameters. Extensive experiments show that SPL outperforms the stateof-the-art SSL methods on all the benchmarks by a large margin. Moreover, experiments demonstrate that SPL can be integrated into the most popular deep SSL networks and be easily extended to handle other cases of class distribution mismatch.

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IJCAI Conference 2020 Conference Paper

Towards Accurate and Robust Domain Adaptation under Noisy Environments

Zhongyi Han
Xian-Jin Gui
Chaoran Cui
Yilong Yin

In non-stationary environments, learning machines usually confront the domain adaptation scenario where the data distribution does change over time. Previous domain adaptation works have achieved great success in theory and practice. However, they always lose robustness in noisy environments where the labels and features of examples from the source domain become corrupted. In this paper, we report our attempt towards achieving accurate noise-robust domain adaptation. We first give a theoretical analysis that reveals how harmful noises influence unsupervised domain adaptation. To eliminate the effect of label noise, we propose an offline curriculum learning for minimizing a newly-defined empirical source risk. To reduce the impact of feature noise, we propose a proxy distribution based margin discrepancy. We seamlessly transform our methods into an adversarial network that performs efficient joint optimization for them, successfully mitigating the negative influence from both data corruption and distribution shift. A series of empirical studies show that our algorithm remarkably outperforms state of the art, over 10% accuracy improvements in some domain adaptation tasks under noisy environments.

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