JBHI Journal 2026 Journal Article
$\text{P}^\text{2}$RS: A Quantitative Rating Scale for Pain Assessment based on Pulse Wave Characterization
- Yue He
- Yi Sun
- Ke Sun
- Wei Bin
- Quan Wang
- Heng Yang
- Xinxin Li
For pain intensity assessment, currently there are mainly 11 rating scales, from primitive Visual Analog Scale (VAS) to elaborate Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP). However, they all depend on a self-report mechanism, making their results so subjective that the consistency, comparability and reference value are barely satisfactory. Inspired by the phenomenon that discomfort may give rise to the throbbing of radial artery, we develop an objective rating scale innovatively, quantifying the severity of pain by the degree of “lateral instability” of an arterial pulse wave. In attempting to monitor this lateral instability, a sort of ultra-small piezoresistive pressure sensor is fabricated in an area of 0. 4 × 0. 4 $\text{mm}^\text{2}$. With 18 of such sensors, we build a flexible tactile sensing dense-array with a pitch of only 0. 65 mm. Overlying the radial artery perpendicularly to the blood flow direction, the dense-array succeeds in observing the cross-section of a pulse wave. The barycenter of the cross-section of each wave cycle is taken as the feature point to represent its lateral shape and drift. The standard deviation of the barycenters' horizontal coordinates is thereby calculated as the pulsatile perceptual rating scale ( $\text{P}^\text{2}$ RS) to reflect the degree of lateral instability, that is, our scale of pain intensity. Among 86 clinical samples, the pain threshold is 0. 11, which is concluded by a binary classification model based on a support vector machine. In terms of its consistency with previous rating scales, the average correlation coefficient reaches 0. 804 among 43 pain samples.