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Yue Cui

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12 papers
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12

AAAI Conference 2026 Conference Paper

Active Multi-source Domain Adaptation for Multimodal Fake News Detection

  • Yanping Chen
  • Weijie Shi
  • Mengze Li
  • Yue Cui
  • Jiaming Li
  • Ruiyuan Zhang
  • Hao Chen
  • Hanghui Guo

Multimodal fake news detection plays a crucial role in combating online misinformation. The inherent domain diversity of news in the real world has driven the development of cross-domain detection methods. However, these detection methods either suffer from significant performance degradation due to semantic and deception pattern shifts between the training (source) and test (target) domains or heavily rely on annotated labels. To address the problems, we propose ADOSE, an active multi-source domain adaptation framework for multimodal fake news detection which actively annotates a small subset of target samples to improve detection performance. Specifically, for domain shifts, we design a multi-expert classifier network based on refined features to comprehensively capture and adapt to the semantic space and deception patterns of news across different domains. To maximize adaptation performance with limited annotation cost, we propose a least-disagree uncertainty selector equipped with a diversity calculator for selecting the most informative samples. The selector leverages the uncertainty of inconsistent predictions before and after perturbations by multiple classifiers as an indicator of unfamiliar samples. It further incorporates diversity scores derived from multi-view features to ensure the chosen samples achieve maximal coverage of target domain features. The extensive experiments on multiple datasets show that ADOSE outperforms existing domain adaptation methods by 2.45% ~ 9.1%, indicating the superiority of our model.

EAAI Journal 2026 Journal Article

Dual-channel machine learning proxy for pseudo-two-dimensional model with enhanced extrapolation correction

  • Yue Cui
  • Yaxuan Wang
  • Shilong Guo
  • Liang Deng
  • Junfu Li
  • Lei Zhao
  • Zhenbo Wang

Physics-based electrochemical models are essential for analyzing and predicting the performance of lithium metal batteries (LMBs), yet their high computational cost restricts their use in real-time applications. To overcome this limitation, a dual-channel agent model (DCAM) is proposed, which decouples the mapping between electrochemical parameters and discharge duration and voltage profile, serving as an efficient surrogate for the pseudo-two-dimensional (P2D) model. Unlike physics-constrained or purely data-driven approaches, DCAM does not rely on explicit physical equations but rather bypasses regions with poor generalization, enabling fast and accurate extrapolation from partial discharge data. Furthermore, a hybrid modeling framework is developed by embedding a multilayer perceptron (MLP) into the Butler–Volmer (B–V) kinetics, replacing the iterative Newton process and thereby improving computational efficiency. Experimental and simulation results demonstrate that the proposed framework accurately reproduces the P2D voltage behavior and achieves high-fidelity extrapolation and robustness under limited-data conditions.

AAAI Conference 2026 Conference Paper

TIV: Thought Injection via Vectors for Efficient Reasoning in Large Reasoning Models

  • Yi Cao
  • Weijie Shi
  • Wei-Jie Xu
  • Yucheng Shen
  • Yue Cui
  • Hanghui Guo
  • Shimin Di
  • Ziyi Liu

Large Reasoning Models (LRMs) have recently demonstrated impressive performance across a range of reasoning tasks by generating intermediate thoughts. However, these models can suffer from overthinking—generating excessive tokens that contribute little to final accuracy while increasing inference cost. To mitigate this, we propose TIV (Thought Injection via Vectors), an innovative framework that compresses token-level reasoning into compact vectors without sacrificing performance. Rather than generating explicit thoughts, TIV injects learnable vectors into the post-attention hidden states of the final token across Transformer layers, enabling implicit and lightweight reasoning. We further introduce a two-stage reinforcement learning strategy: the first stage calibrates the model's reasoning distribution, and the second distills it into a vector-based policy optimized for both accuracy and brevity. Experiments on three reasoning benchmarks show that TIV preserves over 99% of the original accuracy while reducing output length by more than 65% on average, reaching up to 80% in some cases. Moreover, TIV consistently achieves superior trade-offs between accuracy and efficiency compared to existing methods, distinguishing itself as a state-of-the-art (SOTA) approach for efficient reasoning in LRMs.

NeurIPS Conference 2025 Conference Paper

Semantic-guided Diverse Decoding for Large Language Model

  • Weijie Shi
  • Yue Cui
  • Yaguang Wu
  • Jingzhi Fang
  • Shibo Zhang
  • Mengze Li
  • Sirui Han
  • Jia Zhu

Diverse decoding of large language models is crucial for applications requiring multiple semantically distinct responses, yet existing methods primarily achieve lexical rather than semantic diversity. This limitation significantly constrains Best-of-N strategies, group-based reinforcement learning, and data synthesis. While temperature sampling and diverse beam search modify token distributions or apply n-gram penalties, they fail to ensure meaningful semantic differentiation. We introduce Semantic-guided Diverse Decoding (SemDiD), operating directly in embedding space that balances quality with diversity through three complementary mechanisms: orthogonal directional guidance, dynamic inter-group repulsion, and position-debiased probability assessment. SemDiD harmonizes these competing objectives using adaptive gain functions and constraint optimization, ensuring both quality thresholds and maximal semantic differentiation. Experiments show SemDiD consistently outperforms existing methods, improving Best-of-N coverage by 1. 4-5. 2% across diverse tasks and accelerating RLHF training convergence by 15% while increasing accuracy by up to 2. 1%.

YNICL Journal 2022 Journal Article

Specific structuro-metabolic pattern of thalamic subnuclei in fatal familial insomnia: A PET/MRI imaging study

  • Kexin Xie
  • Yaojing Chen
  • Min Chu
  • Yue Cui
  • Zhongyun Chen
  • Jing Zhang
  • Li Liu
  • Donglai Jing

BACKGROUND: Dysfunction of the thalamus has been proposed as a core mechanism of fatal familial insomnia. However, detailed metabolic and structural alterations in thalamic subnuclei are not well documented. We aimed to address the multimodal structuro-metabolic pattern at the level of the thalamic nuclei in fatal familial insomnia patients, and investigated the clinical presentation of primary thalamic alterations. MATERIALS AND METHODS: Five fatal familial insomnia patients and 10 healthy controls were enrolled in this study. All participants underwent neuropsychological assessments, polysomnography, electroencephalogram, and cerebrospinal fluid tests. MRI and fluorodeoxyglucose PET were acquired on a hybrid PET/MRI system. Structural and metabolic changes were compared using voxel-based morphometry analyses and standardized uptake value ratio analyses, focusing on thalamic subnuclei region of interest analyses. Correlation analysis was conducted between gray matter volume and metabolic decrease ratios, and clinical features. RESULTS: The whole-brain analysis showed that gray matter volume decline was confined to the bilateral thalamus and right middle temporal pole in fatal familial insomnia patients, whereas hypometabolism was observed in the bilateral thalamus, basal ganglia, and widespread cortices, mainly in the forebrain. In the regions of interest analysis, gray matter volume and metabolism decreases were prominent in bilateral medial dorsal nuclei, anterior nuclei, and the pulvinar, which is consistent with neuropathological and clinical findings. A positive correlation was found between gray matter volume and metabolic decrease ratios. CONCLUSIONS: Our study revealed specific structuro-metabolic pattern of fatal familial insomnia that demonstrated the essential roles of medial dorsal nuclei, anterior nuclei, and pulvinar, which may be a potential biomarker in diagnosis. Also, primary thalamic subnuclei alterations may be correlated with insomnia, neuropsychiatric, and autonomic symptoms sparing primary cortical involvement.

YNICL Journal 2022 Journal Article

Thalamic-insomnia phenotype in E200K Creutzfeldt–Jakob disease: A PET/MRI study

  • Hong Ye
  • Min Chu
  • Zhongyun Chen
  • Kexin Xie
  • Li Liu
  • Haitian Nan
  • Yue Cui
  • Jing Zhang

BACKGROUND: Insomnia and thalamic involvement were frequently reported in patients with genetic Creutzfeldt-Jakob disease (gCJD) with E200K mutations, suggesting E200K might have discrepancy with typical sporadic CJD (sCJD). The study aimed to explore the clinical and neuroimage characteristics of genetic E200K CJD patients by comprehensive neuroimage analysis. METHODS: Six patients with gCJD carried E200K mutation on Prion Protein (PRNP) gene, 13 patients with sporadic CJD, and 22 age- and sex-matched normal controls were enrolled in the study. All participants completed a hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) examination. Signal intensity on diffusion-weighted imaging (DWI) and metabolism on PET were visually rating analyzed, statistical parameter mapping analysis was performed on PET and 3D-T1 images. Clinical and imaging characteristics were compared between the E200K, sCJD, and control groups. RESULTS: There was no group difference in age or gender among the E200K, sCJD, and control groups. Insomnia was a primary complaint in patients with E200K gCJD (4/2 versus 1/12, p = 0.007). Hyperintensity on DWI and hypometabolism on PET of the thalamus were observed during visual rating analysis of images in patients with E200K gCJD. Gray matter atrophy (uncorrected p < 0.001) and hypometabolism (uncorrected p < 0.001) of the thalamus were more pronounced in patients with E200K gCJD. CONCLUSION: The clinical and imaging characteristics of patients with gCJD with PRNP E200K mutations manifested as a thalamic-insomnia phenotype. PET is a sensitive approach to help identify the functional changes in the thalamus in prion disease.

YNIMG Journal 2022 Journal Article

The human mediodorsal thalamus: Organization, connectivity, and function

  • Kaixin Li
  • Lingzhong Fan
  • Yue Cui
  • Xuehu Wei
  • Yini He
  • Jiyue Yang
  • Yuheng Lu
  • Wen Li

The human mediodorsal thalamic nucleus (MD) is crucial for higher cognitive functions, while the fine anatomical organization of the MD and the function of each subregion remain elusive. In this study, using high-resolution data provided by the Human Connectome Project, an anatomical connectivity-based method was adopted to unveil the topographic organization of the MD. Four fine-grained subregions were identified in each hemisphere, including the medial (MDm), central (MDc), dorsal (MDd), and lateral (MDl), which recapitulated previous cytoarchitectonic boundaries from histological studies. The subsequent connectivity analysis of the subregions also demonstrated distinct anatomical and functional connectivity patterns, especially with the prefrontal cortex. To further evaluate the function of MD subregions, partial least squares analysis was performed to examine the relationship between different prefrontal-subregion connectivity and behavioral measures in 1012 subjects. The results showed subregion-specific involvement in a range of cognitive functions. Specifically, the MDm predominantly subserved emotional-cognition domains, while the MDl was involved in multiple cognitive functions especially cognitive flexibility and inhibition. The MDc and MDd were correlated with fluid intelligence, processing speed, and emotional cognition. In conclusion, our work provides new insights into the anatomical and functional organization of the MD and highlights the various roles of the prefrontal-thalamic circuitry in human cognition.

YNICL Journal 2018 Journal Article

Subdivisions of the posteromedial cortex in disorders of consciousness

  • Yue Cui
  • Ming Song
  • Darren M. Lipnicki
  • Yi Yang
  • Chuyang Ye
  • Lingzhong Fan
  • Jing Sui
  • Tianzi Jiang

Evidence suggests that disruptions of the posteromedial cortex (PMC) and posteromedial corticothalamic connectivity contribute to disorders of consciousness (DOCs). While most previous studies treated the PMC as a whole, this structure is functionally heterogeneous. The present study investigated whether particular subdivisions of the PMC are specifically associated with DOCs. Participants were DOC patients, 21 vegetative state/unresponsive wakefulness syndrome (VS/UWS), 12 minimally conscious state (MCS), and 29 healthy controls. Individual PMC and thalamus were divided into distinct subdivisions by their fiber tractograpy to each other and default mode regions, and white matter integrity and brain activity between/within subdivisions were assessed. The thalamus was represented mainly in the dorsal and posterior portions of the PMC, and the white matter tracts connecting these subdivisions to the thalamus had less integrity in VS/UWS patients than in MCS patients and healthy controls. In addition, these tracts had less integrity in DOC patients who did not recover after 12 months than in patients who did. The structural substrates were validated by resting state fMRI finding impaired functional activity within these PMC subdivisions. This study is the first to show that tracts from dorsal and posterior subdivisions of the PMC to the thalamus contribute to DOCs.

YNIMG Journal 2015 Journal Article

The cortical surface area of the insula mediates the effect of DBH rs7040170 on novelty seeking

  • Jin Li
  • Yue Cui
  • Karen Wu
  • Bing Liu
  • Yun Zhang
  • Chao Wang
  • Tianzi Jiang

Novelty seeking (NS) is a personality trait important for adaptive functioning, but an excessive level of NS has been linked to psychiatric disorders such as ADHD and substance abuse. Previous research has investigated separately the neural and genetic bases of the NS trait, but results were mixed and neural and genetic bases have yet to be examined within the same study. In this study, we examined the interrelationships among the dopamine beta-hydroxylase (DBH) gene, brain structure, and the NS trait in 359 healthy Han Chinese subjects. We focused on the DBH gene because it encodes a key enzyme for dopamine metabolism, NS is believed to be related to the dopaminergic system and has been reported associated with DBH variation. Results showed a significant positive association between the cortical surface area of the left insula and NS score. Furthermore, the DBH genetic polymorphism at the SNP rs7040170 was strongly associated with both the surface area of the left insula and NS score, with G carriers having a larger left insula surface area and a higher NS score than AA homozygotes. Subsequent path analysis suggested that the insula partially mediated the association between the DBH gene and the NS trait. Our data provided the first evidence for the involvement of the insula in the dopamine–NS relationship. Future studies of molecular mechanisms underlying the NS personality trait and related psychiatric disorders should consider the mediation effect of the neural structure.

YNIMG Journal 2013 Journal Article

Longitudinal changes in sulcal morphology associated with late-life aging and MCI

  • Tao Liu
  • Perminder S. Sachdev
  • Darren M. Lipnicki
  • Jiyang Jiang
  • Yue Cui
  • Nicole A. Kochan
  • Simone Reppermund
  • Julian N. Trollor

The present study investigated changes in sulcal morphology associated with late-life aging and mild cognitive impairment (MCI). Participants were 219 community-dwelling 70–90year-olds from the Sydney Memory and Ageing Study; all had MRI scans and were classified as having normal cognition (NC) or MCI at each of waves 1 and 2, two years apart. Automated methods were used to calculate a global sulcal index (g-SI), widths of five prominent sulci, and regional cortical thickness. There were significant longitudinal declines in g-SI and increases in sulcal width among the entire sample, but the rate of change differed among cognitive subgroups. Participants with MCI at both waves (persisting MCI) showed accelerated sulcal widening, particularly for the superior frontal and superior temporal sulci. The sulcal morphology of participants who reverted from MCI to NC was more consistent with stable NC than persisting MCI. Overall cortical thickness decreased between waves similarly across the subgroups. While changes in sulcal morphology are characteristic of normal late-life aging, they are accelerated in individuals with MCI (in contrast to changes in cortical thickness). Sulcal measures also differentiate between persistent MCI and MCI that reverts to NC, and may thus help in predicting the prognosis of MCI patients.

YNIMG Journal 2012 Journal Article

Automated detection of amnestic mild cognitive impairment in community-dwelling elderly adults: A combined spatial atrophy and white matter alteration approach

  • Yue Cui
  • Wei Wen
  • Darren M. Lipnicki
  • Mirza Faisal Beg
  • Jesse S. Jin
  • Suhuai Luo
  • Wanlin Zhu
  • Nicole A. Kochan

Amnestic mild cognitive impairment (aMCI) is a syndrome widely considered to be prodromal Alzheimer's disease. Accurate diagnosis of aMCI would enable earlier treatment, and could thus help minimize the prevalence of Alzheimer's disease. The aim of the present study was to evaluate a magnetic resonance imaging-based automated classification schema for identifying aMCI. This was carried out in a sample of community-dwelling adults aged 70–90years old: 79 with a clinical diagnosis of aMCI and 204 who were cognitively normal. Our schema was novel in using measures of both spatial atrophy, derived from T1-weighted images, and white matter alterations, assessed with diffusion tensor imaging (DTI) tract-based spatial statistics (TBSS). Subcortical volumetric features were extracted using a FreeSurfer-initialized Large Deformation Diffeomorphic Metric Mapping (FS+LDDMM) segmentation approach, and fractional anisotropy (FA) values obtained for white matter regions of interest. Features were ranked by their ability to discriminate between aMCI and normal cognition, and a support vector machine (SVM) selected an optimal feature subset that was used to train SVM classifiers. As evaluated via 10-fold cross-validation, the classification performance characteristics achieved by our schema were: accuracy, 71. 09%; sensitivity, 51. 96%; specificity, 78. 40%; and area under the curve, 0. 7003. Additionally, we identified numerous socio-demographic, lifestyle, health and other factors potentially implicated in the misclassification of individuals by our schema and those previously used by others. Given its high level of performance, our classification schema could facilitate the early detection of aMCI in community-dwelling elderly adults.

YNIMG Journal 2012 Journal Article

Predicting the development of mild cognitive impairment: A new use of pattern recognition

  • Yue Cui
  • Perminder S. Sachdev
  • Darren M. Lipnicki
  • Jesse S. Jin
  • Suhuai Luo
  • Wanlin Zhu
  • Nicole A. Kochan
  • Simone Reppermund

While the conversion from mild cognitive impairment to Alzheimer's disease has received much recent attention, the transition from normal cognition to mild cognitive impairment is largely unexplored. The present pattern recognition study addressed this by using neuropsychological test scores and neuroimaging morphological measures to predict the later development of mild cognitive impairment in cognitively normal community-dwelling individuals aged 70–90years. A feature selection algorithm chose a subset of neuropsychological and FreeSurfer-derived morphometric features that optimally differentiated between individuals who developed mild cognitive impairment and individuals who remained cognitively normal. Support vector machines were used to train classifiers and test prediction performance, which was evaluated via 10-fold cross-validation to reduce variability. Prediction performance was greater when using a combination of neuropsychological scores and morphological measures than when using either of these alone. Results for the combined method were: accuracy 78. 51%, sensitivity 73. 33%, specificity 79. 75%, and an area under the receiver operating characteristic curve of 0. 841. Of all the features investigated, memory performance and measures of the prefrontal cortex and parietal lobe were the most discriminative. Our prediction method offers the potential to detect elderly individuals with apparently normal cognition at risk of imminent cognitive decline. Identification at this stage will facilitate the early start of interventions designed to prevent or slow the development of Alzheimer's disease and other dementias.