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Yu Guo

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10 papers
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10

AAAI Conference 2026 Conference Paper

Physically-Based LiDAR Smoke Simulation for Robust 3D Object Detection

  • Shijun Zheng
  • Yu Guo
  • Weiquan Liu
  • Yu Zang
  • Siqi Shen
  • Ming Cheng
  • Cheng Wang

3D object detection in adverse weather is crucial for autonomous driving, especially in smoke where LiDAR data becomes sparse and noisy. Due to the lack of real smoke data, this paper introduces a physics-based simulation framework to generate realistic LiDAR point clouds of smoke and augment large-scale driving datasets. First, we present a 3D fluid dynamics-based smoke simulation framework in Unity, which models the realistic spatial diffusion and temporal evolution of smoke particles. Coupled with a physically accurate LiDAR perception module, our system captures complex light interactions—such as beam attenuation, scattering, and multi-path effects—to generate high-fidelity, physically consistent smoke point clouds. Second, we propose a range image-based data fusion strategy that seamlessly integrates the simulated smoke point clouds into large-scale real-world LiDAR datasets (e.g., Waymo). This approach accurately emulates LiDAR scanning characteristics and naturally incorporates occlusion effects, enabling realistic smoke integration without compromising spatial consistency. To validate our approach, we collect a real-world LiDAR smoke dataset (LiSmoke) and conduct extensive experiments using state-of-the-art 3D detectors. Results demonstrate that models trained with our augmented synthetic data achieve significant improvements in smoke-affected scenarios, while maintaining competitive performance in clear-weather conditions. Our work provides a cost-effective solution for enhancing perception robustness in safety-critical environments.

AAAI Conference 2025 Conference Paper

A New Adversarial Perspective for LiDAR-based 3D Object Detection

  • Shijun Zheng
  • Weiquan Liu
  • Yu Guo
  • Yu Zang
  • Siqi Shen
  • Cheng Wang

Autonomous vehicles (AVs) rely on LiDAR sensors for environmental perception and decision-making in driving scenarios. However, ensuring the safety and reliability of AVs in complex environments remains a pressing challenge. To address this issue, we introduce a real-world dataset (ROLiD) comprising LiDAR-scanned point clouds of two random objects: water mist and smoke. In this paper, we introduce a novel adversarial perspective by proposing an attack framework that utilizes water mist and smoke to simulate environmental interference. Specifically, we propose a point cloud sequence generation method using a motion and content decomposition generative adversarial network named PCS-GAN to simulate the distribution of random objects. Furthermore, leveraging the simulated LiDAR scanning characteristics implemented with Range Image, we examine the effects of introducing random object perturbations at various positions on the target vehicle. Extensive experiments demonstrate that adversarial perturbations based on random objects effectively deceive vehicle detection and reduce the recognition rate of 3D object detection models.

TMLR Journal 2025 Journal Article

A Survey on Large Language Model-Based Social Agents in Game-Theoretic Scenarios

  • Xiachong Feng
  • Longxu Dou
  • Minzhi Li
  • Qinghao Wang
  • Yu Guo
  • Haochuan Wang
  • Chang Ma
  • Lingpeng Kong

Game-theoretic scenarios have become pivotal in evaluating the social intelligence of Large Language Model (LLM)-based social agents. While numerous studies have explored these agents in such settings, there is a lack of a comprehensive survey summarizing the current progress. To address this gap, we systematically review existing research on LLM-based social agents within game-theoretic scenarios. Our survey organizes the findings into three core components: Game Framework, Social Agent, and Evaluation Protocol. The game framework encompasses diverse game scenarios, ranging from choice-focusing to communication-focusing games. The social agent part explores agents' preferences, beliefs, and reasoning abilities, as well as their interactions and synergistic effects on decision-making. The evaluation protocol covers both game-agnostic and game-specific metrics for assessing agent performance. Additionally, we analyze the performance of current social agents across various game scenarios. By reflecting on the current research and identifying future research directions, this survey provides insights to advance the development and evaluation of social agents in game-theoretic scenarios.

NeurIPS Conference 2025 Conference Paper

Neptune-X: Active X-to-Maritime Generation for Universal Maritime Object Detection

  • Yu Guo
  • Shengfeng He
  • Yuxu Lu
  • Haonan An
  • Yihang Tao
  • Huilin Zhu
  • Jingxian Liu
  • Yuguang Fang

Maritime object detection is essential for navigation safety, surveillance, and autonomous operations, yet constrained by two key challenges: the scarcity of annotated maritime data and poor generalization across various maritime attributes (e. g. , object category, viewpoint, location, and imaging environment). To address these challenges, we propose Neptune-X, a data-centric generative-selection framework that enhances training effectiveness by leveraging synthetic data generation with task-aware sample selection. From the generation perspective, we develop X-to-Maritime, a multi-modality-conditioned generative model that synthesizes diverse and realistic maritime scenes. A key component is the Bidirectional Object-Water Attention module, which captures boundary interactions between objects and their aquatic surroundings to improve visual fidelity. To further improve downstream tasking performance, we propose Attribute-correlated Active Sampling, which dynamically selects synthetic samples based on their task relevance. To support robust benchmarking, we construct the Maritime Generation Dataset, the first dataset tailored for generative maritime learning, encompassing a wide range of semantic conditions. Extensive experiments demonstrate that our approach sets a new benchmark in maritime scene synthesis, significantly improving detection accuracy, particularly in challenging and previously underrepresented settings. The code is available at https: //github. com/gy65896/Neptune-X.

IJCAI Conference 2024 Conference Paper

Who Looks like Me: Semantic Routed Image Harmonization

  • Jinsheng Sun
  • Chao Yao
  • Xiaokun Wang
  • Yu Guo
  • Yalan Zhang
  • Xiaojuan Ban

Image harmonization, aiming to seamlessly blend extraneous foreground objects with background images, is a promising and challenging task. Ensuring a synthetic image appears realistic requires maintaining consistency in visual characteristics, such as texture and style, across global and semantic regions. In this paper, We approach image harmonization as a semantic routed style transfer problem, and propose an imageharmonization model by routing semantic similarity explicitly to enhance the consistency of appearance characteristics. To refine calculate the similarity between the composed foreground and background instance, we propose an InstanceSimilarity Evaluation Module(ISEM). To harness analogous semantic information effectively, we further introduceStyle Transfer Block(STB) to establish fine-grained foreground-background semantic correlation. Our method has achieved excellent experimental results on existing datasets and our model outperforms the state-of-the-art by a margin of 0. 45 dB on iHarmony4 dataset.

YNICL Journal 2022 Journal Article

Evaluating iron deposition in gray matter nuclei of patients with unilateral middle cerebral artery stenosis using quantitative susceptibility mapping

  • Huimin Mao
  • Weiqiang Dou
  • Kunjian Chen
  • Xinyu Wang
  • Xinyi Wang
  • Yu Guo
  • Chao Zhang

Iron mediated oxidative stress is involved in the process of brain injury after long-term ischemia. While increased iron deposition in the affected brain regions was observed in animal models of ischemic stroke, potential changes in the brain iron content in clinical patients with cerebral ischemia remain unclear. Quantitative susceptibility mapping (QSM), a non-invasive magnetic resonance imaging technique, can be used to evaluate iron content in the gray matter (GM) nuclei reliably. In this study, we aimed to quantitatively evaluate iron content changes in GM nuclei of patients with long-term unilateral middle cerebral artery (MCA) stenosis/occlusion-related cerebral ischemia using QSM. Forty-six unilateral MCA stenosis/occlusion patients and 38 age-, sex- and education-matched healthy controls underwent QSM. Clinical variables of history of hypertension, diabetes, hyperlipidemia, hyperhomocysteinemia, smoking, and drinking in all patients were evaluated. The iron-related susceptibility of GM nucleus subregions, including the bilateral caudate nucleus (CN), putamen (PU), globus pallidus (GP), thalamus, substantia nigra (SN), red nucleus, and dentate nucleus, was assessed. Susceptibility was compared between the bilateral GM nuclei in patients and controls. Receiver operating characteristic curve analysis was used to evaluate the efficacy of QSM susceptibility in distinguishing patients with unilateral MCA stenosis/occlusion from healthy controls. Multiple linear regression analysis was used to evaluate the relationship between ipsilateral susceptibility levels and clinical variables. Except for the CN, the susceptibility in most bilateral GM nucleus subregions was comparable in healthy controls, whereas for patients with unilateral MCA stenosis/occlusion, the ipsilateral PU, GP, and SN exhibited significantly higher susceptibility than the contralateral side (all P < 0.05). Compared with controls, susceptibility of the ipsilateral PU, GP, and SN and of contralateral PU in patients were significantly increased (all P < 0.05). The area under the curve (AUC) was greater for the ipsilateral PU than for the GP and SN (AUC = 0.773, 0.662 and 0.681; all P < 0.05). Multiple linear regression analysis showed that the increased susceptibility of the ipsilateral PU was significantly associated with hypertension, of the ipsilateral GP associated with smoking, and of the ipsilateral SN associated with diabetes (all P < 0.05). Our findings provide support for abnormal iron accumulation in the GM nuclei after chronic MCA stenosis/occlusion and its correlation with some cerebrovascular disease risk factors. Therefore, iron deposition in the GM nuclei, as measured by QSM, may be a potential biomarker for long-term cerebral ischemia.

YNICL Journal 2021 Journal Article

Time-delay structure predicts clinical scores for patients with disorders of consciousness using resting-state fMRI

  • Bolin Cao
  • Yu Guo
  • Yequn Guo
  • Qiuyou Xie
  • Lixiang Chen
  • Huiyuan Huang
  • Ronghao Yu
  • Ruiwang Huang

BACKGROUND: The detection of intrinsic brain activity (iBA) could assist clinical assessment for disorder of consciousness (DOC) patients. Previous studies have revealed the altered iBA in thalamocortical, frontoparietal, and default mode network in DOC patients using functional connectivity (FC) analysis. However, due to the assumption of synchronized iBA in FC, these studied may be inadequate for understanding the effect of severe brain injury on the temporal organization of iBA and the relationship between temporal organization and clinical feature in DOC patients. Recently, the time delay estimation (TDE) and probabilistic flow estimation (PFE) were proposed to analyze temporal organization, which could provide propagation structure and propagation probability at whole-brain level. METHODS: We applied voxel-wise TDE and PFE to assess propagation structure and propagation probability for the DOC patients and then applied the connectome-based predictive modeling (CPM) to predict clinical scores for patients based on the ROI-wise TDE and PFE. RESULTS: We found that: 1) the DOC patients showed abnormal voxel-wise time delay (TD) and probabilistic flow (PF) in the precentral gyrus, precuneus, middle cingulate cortex, and postcentral gyrus, 2) the range of TD value in the patients was shorter than that in the controls, and 3) the ROI-wise TD had a better predictive performance for clinical scores of the patients compared with that based on ROI-wise PF. CONCLUSION: Our findings may suggest that the propagation structure of iBA could be used to predict clinical scores in DOC patients.

YNICL Journal 2020 Journal Article

Genome-wide association study of white matter hyperintensity volume in elderly persons without dementia

  • Yu Guo
  • Xue-Ning Shen
  • Xiao-He Hou
  • Ya-Nan Ou
  • Yu-Yuan Huang
  • Qiang Dong
  • Lan Tan
  • Jin-Tai Yu

BACKGROUND: White matter hyperintensity has been correlated with cognitive disorders and its genetic predictors remain unclear. Here we conducted a genome-wide association study to identify novel genetic determinants that were correlated with white matter hyperintensity volume (WMHV) among non-demented elders. METHODS: Three hundred and fifty non-Hispanic Caucasian subjects aged 55-80 years were included from the Alzheimer's Disease Neuroimaging Initiative cohort. Associations of WMHV with genetic polymorphisms were explored using multiple linear regression under an additive genetic model. Further studies were conducted to explore the influence of genetic variants on cognition-related phenotypes. RESULTS: ) were identified as suggestive loci linked to WMHV levels. The minor allele of rs7220676 (C) showed association with lower log (WMHV) in a dose-dependent manner. Besides, rs7220676 was correlated with rates of cognitive decline assessed by Mini-mental State Examination and memory scores. CONCLUSIONS: A novel locus near HS3ST3A1 and MIR548H3 genes was associated with WMHV levels and it may be involved in neurodegenerative diseases.

ICRA Conference 2019 Conference Paper

Visual Guidance and Automatic Control for Robotic Personalized Stent Graft Manufacturing

  • Yu Guo
  • Miao Sun
  • Frank Po Wen Lo
  • Benny Lo

Personalized stent graft is designed to treat Abdominal Aortic Aneurysms (AAA). Due to the individual difference in arterial structures, stent graft has to be custom made for each AAA patient. Robotic platforms for autonomous personalized stent graft manufacturing have been proposed in recently which rely upon stereo vision systems for coordinating multiple robots for fabricating customized stent grafts. This paper proposes a novel hybrid vision system for real-time visual-sevoing for personalized stent-graft manufacturing. To coordinate the robotic arms, this system is based on projecting a dynamic stereo microscope coordinate system onto a static wide angle view stereo webcam coordinate system. The multiple stereo camera configuration enables accurate localization of the needle in 3D during the sewing process. The scale-invariant feature transform (SIFT) method and color filtering are implemented for stereo matching and feature identifications for object localization. To maintain the clear view of the sewing process, a visual-servoing system is developed for guiding the stereo microscopes for tracking the needle movements. The deep deterministic policy gradient (DDPG) reinforcement learning algorithm is developed for real-time intelligent robotic control. Experimental results have shown that the robotic arm can learn to reach the desired targets autonomously.

IROS Conference 2012 Conference Paper

A master-slave robotic simulator based on GPUDirect

  • Jianying Li
  • Yu Guo
  • Heye Zhang
  • Yongming Xie

The same as in traditional surgery, surgeons in telerobotic surgery need extensive training to achieve experience and highly accurate instrument manipulation. Traditional training methods like practice in operating room have major drawbacks such as high risk and limited opportunity for which virtual reality (VR) and computer technologies can offer solutions. To accelerate the data transmission speed in our master-slave robotic simulator, GPUDirect was applied to ensure the synchronization and display rate of three computers. By using GPUDirect with InfiniBand card we realized up to 247% performance improvement in data transmission speed on NVIDIA Tesla™ products on different computers compared to that without GPUDirect, which shows that GPUDirect enables better communication between remote GPUs over InfiniBand.