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Yibo Chen

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3 papers
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3

NeurIPS Conference 2025 Conference Paper

CQ-DINO: Mitigating Gradient Dilution via Category Queries for Vast Vocabulary Object Detection

  • Zhichao Sun
  • Huazhang Hu
  • Yidong Ma
  • Gang Liu
  • Yibo Chen
  • Xu Tang
  • Yao Hu
  • Yongchao Xu

With the exponential growth of data, traditional object detection methods are increasingly struggling to handle vast vocabulary object detection tasks effectively. We analyze two key limitations of classification-based detectors: positive gradient dilution, where rare positive categories receive insufficient learning signals, and hard negative gradient dilution, where discriminative gradients are overwhelmed by numerous easy negatives. To address these challenges, we propose CQ-DINO, a category query-based object detection framework that reformulates classification as a contrastive task between object queries and learnable category queries. Our method introduces image-guided query selection, which reduces the negative space by adaptively retrieving top-K relevant categories per image via cross-attention, thereby rebalancing gradient distributions and facilitating implicit hard example mining. Furthermore, CQ-DINO flexibly integrates explicit hierarchical category relationships in structured datasets (e. g. , V3Det) or learns implicit category correlations via self-attention in generic datasets (e. g. , COCO). Experiments demonstrate that CQ-DINO achieves superior performance on the challenging V3Det benchmark (surpassing previous methods by 2. 1% AP) while maintaining competitiveness in COCO. Our work provides a scalable solution for real-world detection systems requiring wide category coverage.

NeurIPS Conference 2025 Conference Paper

InstanceAssemble: Layout-Aware Image Generation via Instance Assembling Attention

  • Qiang Xiang
  • Shuang Sun
  • Binglei Li
  • Dejia Song
  • Huaxia Li
  • Yibo Chen
  • Xu Tang
  • Yao Hu

Diffusion models have demonstrated remarkable capabilities in generating high-quality images. Recent advancements in Layout-to-Image (L2I) generation have leveraged positional conditions and textual descriptions to facilitate precise and controllable image synthesis. Despite overall progress, current L2I methods still exhibit suboptimal performance. Therefore, we propose InstanceAssemble, a novel architecture that incorporates layout conditions via instance-assembling attention, enabling position control with bounding boxes (bbox) and multimodal content control including texts and additional visual content. Our method achieves flexible adaption to existing DiT-based T2I models through light-weighted LoRA modules. Additionally, we propose a Layout-to-Image benchmark, Denselayout, a comprehensive benchmark for layout-to-image generation, containing 5k images with 90k instances in total. We further introduce Layout Grounding Score (LGS), an interpretable evaluation metric to more precisely assess the accuracy of L2I generation. Experiments demonstrate that our InstanceAssemble method achieves state-of-the-art performance under complex layout conditions, while exhibiting strong compatibility with diverse style LoRA modules. The code and pretrained models are publicly available at \url{https: //github. com/FireRedTeam/InstanceAssemble}.

JBHI Journal 2024 Journal Article

pathCLIP: Detection of Genes and Gene Relations From Biological Pathway Figures Through Image-Text Contrastive Learning

  • Fei He
  • Kai Liu
  • Zhiyuan Yang
  • Yibo Chen
  • Richard D. Hammer
  • Dong Xu
  • Mihail Popescu

In biomedical literature, biological pathways are commonly described through a combination of images and text. These pathways contain valuable information, including genes and their relationships, which provide insight into biological mechanisms and precision medicine. Curating pathway information across the literature enables the integration of this information to build a comprehensive knowledge base. While some studies have extracted pathway information from images and text independently, they often overlook the correspondence between the two modalities. In this paper, we present a pathway figure curation system named pathCLIP for identifying genes and gene relations from pathway figures. Our key innovation is the use of an image-text contrastive learning model to learn coordinated embeddings of image snippets and text descriptions of genes and gene relations, thereby improving curation. Our validation results, using pathway figures from PubMed, showed that our multimodal model outperforms models using only a single modality. Additionally, our system effectively curates genes and gene relations from multiple literature sources. Two case studies on extracting pathway information from literature of non-small cell lung cancer and Alzheimer's disease further demonstrate the usefulness of our curated pathway information in enhancing related pathways in the KEGG database.

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