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Yanping Bao

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EAAI Journal 2023 Journal Article

Defect engineering of fatigue-resistant steels by data-driven models

  • Chao Gu
  • Yanping Bao
  • Sayoojya Prasad
  • Ziyu Lyu
  • Junhe Lian

As inclusions are inevitable from the material-producing processes, an engineering concept regarding multiple features of them is needed for material design. In this study, a unique approach integrating physical-meaningful microstructure-sensitive models with the machine-learning-based data-driven model is proposed to reveal the complex relationship between the fatigue life of materials with intrinsic features of inclusions including size, stiffness, thermal properties, and extrinsic stress amplitudes. This high-fidelity presentation of the relation of these variables enables a detailed and systematic analysis of the effects of inclusions on fatigue life. The data-based phase map provides a designing envelope of inclusion features for fatigue-resistant steels.

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YNICL Journal 2020 Journal Article

Disruption of the structural and functional connectivity of the frontoparietal network underlies symptomatic anxiety in late-life depression

  • Hui Li
  • Xiao Lin
  • Lin Liu
  • Sizhen Su
  • Ximei Zhu
  • Yongbo Zheng
  • Weizhen Huang
  • Jianyu Que

The present study investigated functional connectivity and white matter integrity of the fronto-parietal network (FPN) to reveal the neural mechanisms that underlie late-life depression (LLD). Fifty patients with LLD and 40 non-depressed controls were included in the study. A multi-parametric approach was used by applying independent component analysis (ICA) to estimate functional connectivity of the FPN and by applying tract-based spatial statistics to examine white-matter integrity in tracts to the FPN. Patients with LLD exhibited functional abnormalities in the right inferior frontal gyrus, middle frontal gyrus, and inferior parietal gyrus and lower white matter fractional anisotropy in the right inferior fronto-occipital fasciculus, anterior thalamic radiation, and uncinate fasciculus. Alterations of functional connectivity and white matter fractional anisotropy in these regions were negatively correlated with the severity of symptomatic anxiety in LLD patients. The right inferior frontal gyrus might be a crucial hub in transferring information between these abnormal regions. Significant correlations were found between anxiety symptoms and brain alterations, suggesting that impairments in the FPN network might be involved in symptomatic anxiety in elderly individuals with depression.

Details DOI
v2026.09.13