EAAI Journal 2025 Journal Article
A consistency regularization-based approach integrating anatomical structural relationships and organ category representations for multi-organ segmentation in pigs
- Xiang Pan
- Hang Fan
- Jianlan Wang
- Yan Fu
- Wei Chu
- Weipeng Tai
- Jing Gu
- Jianming Ni
In modern biomedical research and livestock management, accurate multi-organ segmentation in pigs is essential for breeding programs. However, current methods face challenges due to low imaging contrast, size disparities, and organ shape variability. Additionally, the manual annotation of computed tomography (CT) scans is labor-intensive and costly, limiting available labeled samples. To address these issues, we propose a consistency regularization-based network guided by anatomical structural relationships and global organ category representations, specifically designed for multi-organ segmentation using a limited number of annotated CT scan samples from pigs. Specifically, we designed the SpatialLink Gated Recurrent Unit (GRU) module to extract anatomical structural information and capture dynamic spatial relationships between organs, thereby minimizing segmentation biases caused by organ shape variations. Moreover, we developed the Organ Category Coding module and Guidance module, which integrate consistency regularization and attention mechanisms, enabling the network to accurately extract global organ category representations during the decoding phase, even with a small number of labeled samples, significantly improving segmentation consistency across organs of different sizes. Additionally, We are the first to apply the Visual State Space block to multi-organ segmentation in pigs, using it to extract contextual information. Experiments on 60 pigs demonstrate that our method achieves state-of-the-art results, with significant improvements in segmentation accuracy for the gallbladder and bladder, including a 9. 8% and 4. 2% Dice score increase, respectively, and a 12. 4% and 6. 2% boost in Jaccard scores compared to compared with a selection of published methods.