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Xiuyuan Xu

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5 papers
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5

AAAI Conference 2026 Conference Paper

GeoCoBox: Box-supervised 3D Tumor Segmentation via Geometric Co-embedding

  • Tianzhong Lan
  • Zhang Yi
  • Xiuyuan Xu
  • Min Zhu

Data economics drives AI by optimizing data usage, reducing costs, and enhancing efficiency. In 3D tumor segmentation, efficiency is crucial due to the high demand for labor-intensive manual annotations. Box-supervised segmentation offers a promising alternative but is constrained by tumor morphology complexity and boundary ambiguity. In this paper, we propose a novel 3D tumor segmentation model that integrates both positional and embedding features to facilitate inter-task collaboration. We introduce an Anatomical-Driven Class Activation Map to predefine the complex tumor morphology prior, which is further refined by our Geometric Pixel Co-embedding Learner. This learner utilizes contrastive learning to encode semantic information between center and edge pixels, enhancing pixel clustering and progressively refining tumor boundary segmentation in a coarse-to-fine manner. Our approach outperforms existing box-supervised methods in segmentation performance, with extensive experiments on four tumor datasets demonstrating significant improvements. This work provides a cost-effective and efficient solution for tumor segmentation, advancing the application of data economics in medical imaging.

AAAI Conference 2026 Conference Paper

Mitigating Entity Hallucinations in 3D Radiology Report Generation via Dual-Stream Alignment

  • Lingyu Zhou
  • Yue Yu
  • Zhang Yi
  • Xiuyuan Xu

Entity hallucination poses a major challenge in radiology report generation (RRG), particularly for 3D CT scans where complex spatial contexts amplify factual errors. To address this, medical entity phrases serve as key carriers for multi-modal prompting, integrating expert knowledge into the vision-language model. Current methods use unified cross-attention for volume-phrase alignment, failing to account for anatomical specificity during the alignment process. In this work, we introduce the Dual-stream Entity Alignment Reporting network (DEAR) that separately models organ and lesion entities to resolve anatomical bias. Specifically, the dual-stream entity aligner is designed to partition medical entity phrases into organ and lesion streams, feeding them into separate cross-attention blocks in parallel to achieve fine-grained volume–phrase alignment. For structurally regular and spatially stable organ entities, an organ-guided cross-attention (OGCA) block is proposed to enforce structural consistency by retrieving the top-k voxel tokens via volume–phrase similarity and preserving spatial connectivity through morphological dilation. Meanwhile, a lesion-guided cross-attention (LGCA) block is introduced for structurally irregular and spatially variable lesion entities, enhancing anomaly sensitivity through phrase-weighted attention and refining discriminative boundaries via 3D residual Laplacian filtering. Experiments demonstrate that DEAR significantly reduces entity hallucinations and improves clinical factuality in 3D RRG benchmarks.

AAAI Conference 2026 Conference Paper

RoSE: A Role Correlation Structure-Enhanced Model for Multi-Event Argument Extraction

  • Geting Huang
  • Jilong Zhang
  • Kai Zhou
  • Zhang Yi
  • Xiuyuan Xu

Event co-occurrences have been proven effective for event argument extraction (EAE) in previous studies; however, few have considered intra- and inter-event role correlations. Since role varies among different event types, event structure heterogeneity and overlap pose significant challenges to EAE. To address this issue, we propose a Role Correlation Structure-Enhanced model for Multi-Event Argument Extraction (RoSE), capable of capturing both heterogeneity and overlap of event structures through modeling role correlations. The proposed RoSE model employs a joint context-prompts input, role-centric graph-guided encoder (RoGE), and role-specific information fusion (RoIF). The RoGE is designed to enhance the intra- and inter-event role correlation between prompts and their corresponding event contexts. The RoIF module utilizes intra-event role information to improve multi-event arguments extraction. Extensive experiments on four widely-used benchmarks (RAMS, WikiEvents, MLEE, and ACE05) demonstrate that our proposed approach achieves state-of-the-art performance, validating the effectiveness of incorporating both intra- and inter-event role correlations.

JBHI Journal 2024 Journal Article

ICNoduleNet: Enhancing Pulmonary Nodule Detection Performance on Sharp Kernel CT Imaging

  • Tianzhong Lan
  • Fanxin Zeng
  • Zhang Yi
  • Xiuyuan Xu
  • Min Zhu

Thoracic computed tomography (CT) currently plays the primary role in pulmonary nodule detection, where the reconstruction kernel significantly impacts performance in computer-aided pulmonary nodule detectors. The issue of kernel selection affecting performance has been overlooked in pulmonary nodule detection. This paper first introduces a novel pulmonary nodule detection dataset named Reconstruction Kernel Imaging for Pulmonary Nodule Detection (RKPN) for quantifying algorithm differences between the two imaging types. The dataset contains pairs of images taken from the same patient on the same date, featuring both smooth (B31f) and sharp kernel (B60f) reconstructions. All other imaging parameters and pulmonary nodule labels remain entirely consistent across these pairs. Extensive quantification reveals mainstream detectors perform better on smooth kernel imaging than on sharp kernel imaging. To address suboptimal detection on the sharp kernel imaging, we further propose an image conversion-based pulmonary nodule detector called ICNoduleNet. A lightweight 3D slice-channel converter (LSCC) module is introduced to convert sharp kernel images into smooth kernel images, which can sufficiently learn inter-slice and inter-channel feature information while avoiding introducing excessive parameters. We conduct thorough experiments that validate the effectiveness of ICNoduleNet, it takes sharp kernel images as input and can achieve comparable or even superior detection performance to the baseline that uses the smooth kernel images. The evaluation shows promising results and proves the effectiveness of ICNoduleNet.

JBHI Journal 2020 Journal Article

MediMLP: Using Grad-CAM to Extract Crucial Variables for Lung Cancer Postoperative Complication Prediction

  • Tao He
  • Jixiang Guo
  • Nan Chen
  • Xiuyuan Xu
  • Zihuai Wang
  • Kaiyu Fu
  • Lunxu Liu
  • Zhang Yi

Lung cancer postoperative complication prediction (PCP) is significant for decreasing the perioperative mortality rate after lung cancer surgery. In this paper we concentrate on two PCP tasks: (1) the binary classification for predicting whether a patient will have postoperative complications; and (2) the three-class multi-label classification for predicting which postoperative complication a patient will experience. Furthermore, an important clinical requirement of PCP is the extraction of crucial variables from electronic medical records. We propose a novel multi-layer perceptron (MLP) model called medical MLP (MediMLP) together with the gradient-weighted class activation mapping (Grad-CAM) algorithm for lung cancer PCP. The proposed MediMLP, which involves one locally connected layer and fully connected layers with a shortcut connection, simultaneously extracts crucial variables and performs PCP tasks. The experimental results indicated that MediMLP outperformed normal MLP on two PCP tasks and had comparable performance with existing feature selection methods. Using MediMLP and further experimental analysis, we found that the variable of “time of indwelling drainage tube” was very relevant to lung cancer postoperative complications.

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