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Xiaojun Shan

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5 papers

2 author rows

ICML Conference 2025 Conference Paper

EARTH: Epidemiology-Aware Neural ODE with Continuous Disease Transmission Graph

Guancheng Wan
Zewen Liu 0005
Xiaojun Shan
Max S. Y. Lau
B. Aditya Prakash
Wei Jin 0009

Effective epidemic forecasting is critical for public health strategies and efficient medical resource allocation, especially in the face of rapidly spreading infectious diseases. However, existing deep-learning methods often overlook the dynamic nature of epidemics and fail to account for the specific mechanisms of disease transmission. In response to these challenges, we introduce an innovative end-to-end framework called Epidemiology-Aware Neural ODE with Continuous Disease Transmission Graph (EARTH) in this paper. To learn continuous and regional disease transmission patterns, we first propose EANO, which seamlessly integrates the neural ODE approach with the epidemic mechanism, considering the complex spatial spread process during epidemic evolution. Additionally, we introduce GLTG to model global infection trends and leverage these signals to guide local transmission dynamically. To accommodate both the global coherence of epidemic trends and the local nuances of epidemic transmission patterns, we build a cross-attention approach to fuse the most meaningful information for forecasting. Through the smooth synergy of both components, EARTH offers a more robust and flexible approach to understanding and predicting the spread of infectious diseases. Extensive experiments show EARTH superior performance in forecasting real-world epidemics compared to state-of-the-art methods. The code is available at https: //github. com/GuanchengWan/EARTH.

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ICML Conference 2025 Conference Paper

EgoPrivacy: What Your First-Person Camera Says About You?

Yijiang Li
Genpei Zhang
Jiacheng Cheng
Yi Li 0051
Xiaojun Shan
Dashan Gao 0001
Jiancheng Lyu
Yuan Li

While the rapid proliferation of wearable cameras has raised significant concerns about egocentric video privacy, prior work has largely overlooked the unique privacy threats posed to the camera wearer. This work investigates the core question: How much privacy information about the camera wearer can be inferred from their first-person view videos? We introduce EgoPrivacy, the first large-scale benchmark for the comprehensive evaluation of privacy risks in egocentric vision. EgoPrivacy covers three types of privacy (demographic, individual, and situational), defining seven tasks that aim to recover private information ranging from fine-grained (e. g. , wearer’s identity) to coarse-grained (e. g. , age group). To further emphasize the privacy threats inherent to egocentric vision, we propose Retrieval-Augmented Attack, a novel attack strategy that leverages ego-to-exo retrieval from an external pool of exocentric videos to boost the effectiveness of demographic privacy attacks. An extensive comparison of the different attacks possible under all threat models is presented, showing that private information of the wearer is highly susceptible to leakage. For instance, our findings indicate that foundation models can effectively compromise wearer privacy even in zero-shot settings by recovering attributes such as identity, scene, gender, and race with 70–80% accuracy. Our code and data are available at https: //github. com/williamium3000/ego-privacy.

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ICLR Conference 2025 Conference Paper

HQGS: High-Quality Novel View Synthesis with Gaussian Splatting in Degraded Scenes

Xin Lin
Shi Luo
Xiaojun Shan
Xiaoyu Zhou
Chao Ren 0002
Lu Qi 0001
Ming-Hsuan Yang 0001
Nuno Vasconcelos

3D Gaussian Splatting (3DGS) has shown promising results for Novel View Synthesis. However, while it is quite effective when based on high-quality images, its performance declines as image quality degrades, due to lack of resolution, motion blur, noise, compression artifacts, or other factors common in real-world data collection. While some solutions have been proposed for specific types of degradation, general techniques are still missing. To address the problem, we propose a robust HQGS that significantly enhances the 3DGS under various degradation scenarios. We first analyze that 3DGS lacks sufficient attention in some detailed regions in low-quality scenes, leading to the absence of Gaussian primitives in those areas and resulting in loss of detail in the rendered images. To address this issue, we focus on leveraging edge structural information to provide additional guidance for 3DGS, enhancing its robustness. First, we introduce an edge-semantic fusion guidance module that combines rich texture information from high-frequency edge-aware maps with semantic information from images. The fused features serve as prior guidance to capture detailed distribution across different regions, bringing more attention to areas with detailed edge information and allowing for a higher concentration of Gaussian primitives to be assigned to such areas. Additionally, we present a structural cosine similarity loss to complement pixel-level constraints, further improving the quality of the rendered images. Extensive experiments demonstrate that our method offers better robustness and achieves the best results across various degraded scenes. Source code and trained models are publicly available at: \url{https://github.com/linxin0/HQGS}.

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NeurIPS Conference 2024 Conference Paper

AdaNovo: Towards Robust \emph{De Novo} Peptide Sequencing in Proteomics against Data Biases

Jun Xia
Shaorong Chen
Jingbo Zhou
Xiaojun Shan
Wenjie Du
Zhangyang Gao
Cheng Tan
Bozhen Hu

Tandem mass spectrometry has played a pivotal role in advancing proteomics, enabling the high-throughput analysis of protein composition in biological tissues. Despite the development of several deep learning methods for predicting amino acid sequences (peptides) responsible for generating the observed mass spectra, training data biases hinder further advancements of \emph{de novo} peptide sequencing. Firstly, prior methods struggle to identify amino acids with Post-Translational Modifications (PTMs) due to their lower frequency in training data compared to canonical amino acids, further resulting in unsatisfactory peptide sequencing performance. Secondly, various noise and missing peaks in mass spectra reduce the reliability of training data (Peptide-Spectrum Matches, PSMs). To address these challenges, we propose AdaNovo, a novel and domain knowledge-inspired framework that calculates Conditional Mutual Information (CMI) between the mass spectra and amino acids or peptides, using CMI for robust training against above biases. Extensive experiments indicate that AdaNovo outperforms previous competitors on the widely-used 9-species benchmark, meanwhile yielding 3. 6\% - 9. 4\% improvements in PTMs identification. The supplements contain the code.

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NeurIPS Conference 2023 Conference Paper

Enhancing Knowledge Transfer for Task Incremental Learning with Data-free Subnetwork

Qiang Gao
Xiaojun Shan
Yuchen Zhang
Fan Zhou

As there exist competitive subnetworks within a dense network in concert with Lottery Ticket Hypothesis, we introduce a novel neuron-wise task incremental learning method, namely Data-free Subnetworks (DSN), which attempts to enhance the elastic knowledge transfer across the tasks that sequentially arrive. Specifically, DSN primarily seeks to transfer knowledge to the new coming task from the learned tasks by selecting the affiliated weights of a small set of neurons to be activated, including the reused neurons from prior tasks via neuron-wise masks. And it also transfers possibly valuable knowledge to the earlier tasks via data-free replay. Especially, DSN inherently relieves the catastrophic forgetting and the unavailability of past data or possible privacy concerns. The comprehensive experiments conducted on four benchmark datasets demonstrate the effectiveness of the proposed DSN in the context of task-incremental learning by comparing it to several state-of-the-art baselines. In particular, DSN enables the knowledge transfer to the earlier tasks, which is often overlooked by prior efforts.

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