JBHI Journal 2014 Journal Article
Accelerometry-Based Home Monitoring for Detection of Nocturnal Hypermotor Seizures Based on Novelty Detection
- Kris Cuppens
- Peter Karsmakers
- Anouk Van de Vel
- Bert Bonroy
- Milica Milosevic
- Stijn Luca
- Tom Croonenborghs
- Berten Ceulemans
Nocturnal home monitoring of epileptic children is often not feasible due to the cumbersome manner of seizure monitoring with the standard method of video/EEG-monitoring. We propose a method for hypermotor seizure detection based on accelerometers attached to the extremities. From the acceleration signals, multiple temporal, frequency, and wavelet-based features are extracted. After determining the features with the highest discriminative power, we classify movement events in epileptic and nonepileptic movements. This classification is only based on a nonparametric estimate of the probability density function of normal movements. Such approach allows us to build patient-specific models to classify movement data without the need for seizure data that are rarely available. If, in the test phase, the probability of a data point (event) is lower than a threshold, this event is considered to be an epileptic seizure; otherwise, it is considered as a normal nocturnal movement event. The mean performance over seven patients gives a sensitivity of 95. 24% and a positive predictive value of 60. 04%. However, there is a noticeable interpatient difference.