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Shanshan Jiang

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5 papers
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5

AAAI Conference 2026 Conference Paper

RetroLM: Retrieval-Augmented KVs for Long-Context Processing

  • Kun Luo
  • Zheng Liu
  • Shitao Xiao
  • Jiabei Chen
  • Hongjin Qian
  • Peitian Zhang
  • Shanshan Jiang
  • Bin Dong

Long-context processing remains a significant challenge for large language models (LLMs). Retrieval-augmented generation (RAG) has recently emerged as a promising approach, enabling LLMs to selectively access relevant information from extended contexts to improve efficiency. However, existing RAG approaches often lag behind other efficient long-context processing methods primarily due to inherent limitations on inaccurate retrieval and fragmented contexts. To address these limitations, we propose RetroLM, a novel RAG framework designed for effective long-context processing. Unlike traditional approaches, RetroLM introduces KV-level retrieval augmentation, which partitions the LLM's KV cache into contiguous pages and performs encoding and decoding operations based on the retrieved KV pages. Built upon this framework, we further develop a specialized retriever for precise retrieval of critical pages and conduct unsupervised post-training to optimize the model’s ability to leverage retrieved information. Compared with traditional RAG, the new approach enhances robustness to retrieval inaccuracy, facilitates effective utilization of fragmented contexts, and saves the cost from repeated context-encoding operations. We conduct extensive evaluations across several popular benchmarks, including LongBench, InfiniteBench, and RULER. RetroLM consistently outperforms existing long-LLMs and RAG-based methods, especially in tasks requiring deep reasoning or extreme context lengths.

YNICL Journal 2022 Journal Article

Learning-based analysis of amide proton transfer-weighted MRI to identify true progression in glioma patients

  • Pengfei Guo
  • Mathias Unberath
  • Hye-Young Heo
  • Charles G. Eberhart
  • Michael Lim
  • Jaishri O. Blakeley
  • Shanshan Jiang

The purpose of this study was to develop and verify a convolutional neural network (CNN)-based deep-learning algorithm to identify tumor progression versus response by adding amide proton transfer-weighted (APTw) MRI data to structural MR images as the proposed model input. 145 scans with 2175 MR instances from 98 patients with malignant glioma (acquired between April 2010 and February 2018) were re-analyzed. An end-to-end classification framework based on a ResNet backbone was developed. The architecture includes a learnable subtraction layer and a hierarchical classification paradigm, and synthesizes information over multiple MR slices using a long short-term memory. Areas under the receiver-operating-characteristic curves (AUCs) were used to assess the impact of adding APTw MRI to structural MRI ( T 1 w, T 2 w, FLAIR, and GdT1w) on classification of tumor response vs. progression, both on the slice- and scan-level. With both APTw and structural MRI data, adding a learnable subtraction layer and a hierarchical classification paradigm to the backbone ResNet model improved the slice-level classification performance from an AUC of 0. 85 to 0. 90. Adding APTw data to structural MR images as input to our proposed CNN classification framework led to an increase in AUCs from 0. 88 to 0. 90 for the slice-level classification (P < 0. 001), and from 0. 85 to 0. 90 for the scan-level classification (P < 0. 05). Generated saliency maps highlighted the vast majority of lesions. Complementing structural MRI sequences with protein-based APTw MRI enhanced CNN-based classification of recurrent glioma at the slice and scan levels. Addition of APTw MRI to structural MRI sequences enhanced CNN-based classification of recurrent glioma at the slice and scan levels.

YNICL Journal 2020 Journal Article

Protein-based amide proton transfer-weighted MR imaging of amnestic mild cognitive impairment

  • Zewen Zhang
  • Caiqing Zhang
  • Jian Yao
  • Xin Chen
  • Fei Gao
  • Shanshan Jiang
  • Weibo Chen
  • Jinyuan Zhou

Amide proton transfer-weighted (APTw) MRI is a novel molecular imaging technique that can noninvasively detect endogenous cellular proteins and peptides in tissue. Here, we demonstrate the feasibility of protein-based APTw MRI in characterizing amnestic mild cognitive impairment (aMCI). Eighteen patients with confirmed aMCI and 18 matched normal controls were scanned at 3 Tesla. The APTw, as well as conventional magnetization transfer ratio (MTR), signal differences between aMCI and normal groups were assessed by the independent samples t-test, and the receiver-operator-characteristic analysis was used to assess the diagnostic performance of APTw. When comparing the normal control group, aMCI brains typically had relatively higher APTw signals. Quantitatively, APTw intensity values were significantly higher in nine of 12 regions of interest in aMCI patients than in normal controls. The largest areas under the receiver-operator-characteristic curves were 0.88 (gray matter in occipital lobe) and 0.82 (gray matter in temporal lobe, white matter in occipital lobe) in diagnosing aMCI patients. On the contrary, MTR intensity values were significantly higher in only three of 12 regions of interest in the aMCI group. Additionally, the age dependency analyses revealed that these cross-sectional APTw/MTR signals had an increasing trend with age in most brain regions for normal controls, but a decreasing trend with age in most brain regions for aMCI patients. Our early results show the potential of the APTw signal as a new imaging biomarker for the noninvasive molecular diagnosis of aMCI.

YNIMG Journal 2019 Journal Article

Quantifying amide proton exchange rate and concentration in chemical exchange saturation transfer imaging of the human brain

  • Hye-Young Heo
  • Zheng Han
  • Shanshan Jiang
  • Michael Schär
  • Peter C.M. van Zijl
  • Jinyuan Zhou

Current chemical exchange saturation transfer (CEST) neuroimaging protocols typically acquire CEST-weighted images, and, as such, do not essentially provide quantitative proton-specific exchange rates (or brain pH) and concentrations. We developed a dictionary-free MR fingerprinting (MRF) technique to allow CEST parameter quantification with a reduced data set. This was accomplished by subgrouping proton exchange models (SPEM), taking amide proton transfer (APT) as an example, into two-pool (water and semisolid macromolecules) and three-pool (water, semisolid macromolecules, and amide protons) models. A variable radiofrequency saturation scheme was used to generate unique signal evolutions for different tissues, reflecting their CEST parameters. The proposed MRF-SPEM method was validated using Bloch-McConnell equation-based digital phantoms with known ground-truth, which showed that MRF-SPEM can achieve a high degree of accuracy and precision for absolute CEST parameter quantification and CEST phantoms. For in-vivo studies at 3 T, using the same model as in the simulations, synthetic Z-spectra were generated using rates and concentrations estimated from the MRF-SPEM reconstruction and compared with experimentally measured Z-spectra as the standard for optimization. The MRF-SPEM technique can provide rapid and quantitative human brain CEST mapping.

IJCAI Conference 2018 Conference Paper

Layered Optical Flow Estimation Using a Deep Neural Network with a Soft Mask

  • Xi Zhang
  • Di Ma
  • Xu Ouyang
  • Shanshan Jiang
  • Lin Gan
  • Gady Agam

Using a layered representation for motion estimation has the advantage of being able to cope with discontinuities and occlusions. In this paper, we learn to estimate optical flow by combining a layered motion representation with deep learning. Instead of pre-segmenting the image to layers, the proposed approach automatically generates a layered representation of optical flow using the proposed soft-mask module. The essential components of the soft-mask module are maxout and fuse operations, which enable a disjoint layered representation of optical flow and more accurate flow estimation. We show that by using masks the motion estimate results in a quadratic function of input features in the output layer. The proposed soft-mask module can be added to any existing optical flow estimation networks by replacing their flow output layer. In this work, we use FlowNet as the base network to which we add the soft-mask module. The resulting network is tested on three well-known benchmarks with both supervised and unsupervised flow estimation tasks. Evaluation results show that the proposed network achieve better results compared with the original FlowNet.

v2026.09.13