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Rizwan Qureshi

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AAAI Conference 2026 Short Paper

DINOv3-Powered Multi-Task Foundation Model for Quantitative Remote Sensing Estimation (Student Abstract)

Zhenyu Yu
Mohd Yamani Idna Idris
Pei Wang
Rizwan Qureshi

Quantitative remote sensing estimation is critical for environmental monitoring, providing continuous measures of vegetation indices, canopy height, and carbon stock. Traditional radiative-transfer models and empirical regressions require expert knowledge and generalize poorly, while deep learning methods remain task-specific. We propose SatelliteCalculator+, a DINOv3-powered multi-task foundation model for continuous regression of spectral and structural variables. The framework combines prompt-driven cross-attentive adapters with lightweight MLP decoders, enabling efficient dense prediction from frozen features. To overcome limited supervision, we synthesize over one million paired samples from SPOT 6/7 imagery using physically defined formulas. On the Open-Canopy dataset, SatelliteCalculator+ achieves competitive accuracy across eight ecological variables while reducing inference cost, demonstrating the promise of self-supervised transformers and scalable multi-task learning for large-scale Earth observation.

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JBHI Journal 2021 Journal Article

Visualization of Protein-Drug Interactions for the Analysis of Drug Resistance in Lung Cancer

Rizwan Qureshi
Mengxu Zhu
Hong Yan

Non-small cell lung cancer (NSCLC) caused by mutation of the epidermal growth factor receptor (EGFR) is a major cause of death worldwide. Tyrosine kinase inhibitors (TKIs) of EGFR have been developed and show promising results at the initial stage of therapy. However, in most cases, their efficacy becomes limited due to the emergence of secondary mutations causing drug resistance after about a year. In this work, we investigated the mechanism of drug resistance due to these mutations. We performed molecular dynamics (MD) simulations of EGFR-drug interactions to obtain Euclidean distance and binding free energy values to analyse drug resistance and visualize drug-protein interactions. A PCA-based method is proposed to find normal, rigid, flexible, and critical residues. We have established a systematic method for the visualization of protein-drug interactions, which provides an effective framework for the analysis of drug resistance in lung cancer at the atomic level.

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