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Qiaoran Chen

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AIIM Journal 2024 Journal Article

FIT-graph: A multi-grained evolutionary graph based framework for disease diagnosis

  • Zizhu Liu
  • Qing Cao
  • Nan Du
  • Huizhen Shu
  • Erheng Zhong
  • Nan Jiang
  • Qiaoran Chen
  • Ying Shen

Early assessment, with the help of machine learning methods, can aid clinicians in optimizing the diagnosis and treatment process, allowing patients to receive critical treatment time. Due to the advantages of effective information organization and interpretable reasoning, knowledge graph-based methods have become one of the most widely used machine learning algorithms for this task. However, due to a lack of effective organization and use of multi-granularity and temporal information, current knowledge graph-based approaches are hard to fully and comprehensively exploit the information contained in medical records, restricting their capacity to make superior quality diagnoses. To address these challenges, we examine and study disease diagnosis applications in-depth, and propose a novel disease diagnosis framework named FIT-Graph. With novel medical multi-grained evolutionary graphs, FIT-Graph efficiently organizes the extracted information from various granularities and time stages, maximizing the retention of valuable information for disease inference and ensuring the comprehensiveness and validity of the final disease inference. We compare FIT-Graph with two real-world clinical datasets from cardiology and respiratory departments with the baseline. The experimental results show that its effect is better than the baseline model, and the baseline performance of the task is improved by about 5% in multiple indices.

AIIM Journal 2021 Journal Article

Practical fine-grained learning based anomaly classification for ECG image

  • Qing Cao
  • Nan Du
  • Li Yu
  • Ming Zuo
  • Jingsheng Lin
  • Nathan Liu
  • Erheng Zhong
  • Zizhu Liu

As a widely used vital sign within cardiology, Electrocardiography (ECG) provides the basis for assessing heart function and diagnosing cardiovascular diseases. Automated anomaly detection for ECG plays an important role in improving patient diagnosis efficiency and reducing healthcare costs. Practically, due to the limits of electronics support or the medical system setting, image is a more common format for large-scale ECG storage in most clinical institutions. To guarantee an automated ECG detection model's scalability and practicality in clinical applications, taking good advantage of ECG images is crucial. However, existing time digital-based discriminative models fail to learn from images effectively for two reasons. First of all, the signals recorded on images have much lower resolution and higher noise, which makes it impractical to extract precise ECG signals following existing techniques. Meanwhile, the differences between abnormal signals are usually subtle, and they may be overwhelmed by the noises in the images as well. Towards this end, we design a novel neural framework that can be directly applied to massive ECG images determining various types of cardiology abnormalities. It classifies fine-grained ECG images based on weakly supervised strategy, in which case only image-level labeling is required. By eliminating the need for part annotations, the proposed method can result in significant savings in annotation time and cost. The effectiveness of the method is demonstrated by experimental results on two real ECG datasets.

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