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Po Yang

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5 papers

1 author row

EAAI Journal 2025 Journal Article

Joint image synthesis and fusion with converted features for Alzheimer’s disease diagnosis

Zhaodong Chen
Mingxia Wang
Fengtao Nan
Yun Yang
Shunbao Li
Menghui Zhou
Jun Qi
Hanwen Wang

The effectiveness of complete multi-modal neuroimaging data in the diagnosis of Alzheimer’s disease has been extensively demonstrated and applied. Dealing with incomplete modalities poses a common challenge in multi-modal neuroimaging diagnosis. The mainstream approaches aim to synthesize missing neuroimaging data in order to make full use of all available samples. However, these methods treat image synthesis and disease diagnosis as two independent tasks, overlooking the potential feature of cross-modality image synthesis for downstream tasks. To this end, we propose the Joint Image Synthesis and Classification Learning method to jointly optimize image synthesis and disease diagnosis using incomplete neuroimaging modalities. Our approach comprises a submodule for synthesizing missing neuroimaging data and a decision fusion submodule that integrates features from different modalities and the high-level/converted features generated during synthesis. Experimental results demonstrate that our joint optimization approach outperforms conventional two-stage methods. Our method is capable of handling arbitrary neuroimaging modality missing scenarios and achieves state-of-the-art performance in both Alzheimer’s Disease identification and mild cognitive impairment conversion classification tasks. Finally, we further explored the importance of different converted features. This highlights the effectiveness of our approach in addressing the challenges of Alzheimer’s Disease diagnosis and provides insights for future research in multi-modal medical image analysis.

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AAAI Conference 2023 Conference Paper

Robust Temporal Smoothness in Multi-Task Learning

Menghui Zhou
Yu Zhang
Yun Yang
Tong Liu
Po Yang

Multi-task learning models based on temporal smoothness assumption, in which each time point of a sequence of time points concerns a task of prediction, assume the adjacent tasks are similar to each other. However, the effect of outliers is not taken into account. In this paper, we show that even only one outlier task will destroy the performance of the entire model. To solve this problem, we propose two Robust Temporal Smoothness (RoTS) frameworks. Compared with the existing models based on temporal relation, our methods not only chase the temporal smoothness information but identify outlier tasks, however, without increasing the computational complexity. Detailed theoretical analyses are presented to evaluate the performance of our methods. Experimental results on synthetic and real-life datasets demonstrate the effectiveness of our frameworks. We also discuss several potential specific applications and extensions of our RoTS frameworks.

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JBHI Journal 2020 Journal Article

Epilepsy Seizure Prediction on EEG Using Common Spatial Pattern and Convolutional Neural Network

Yuan Zhang
Yao Guo
Po Yang
Wei Chen
Benny Lo

Epilepsy seizure prediction paves the way of timely warning for patients to take more active and effective intervention measures. Compared to seizure detection that only identifies the inter-ictal state and the ictal state, far fewer researches have been conducted on seizure prediction because the high similarity makes it challenging to distinguish between the pre-ictal state and the inter-ictal state. In this paper, a novel solution on seizure prediction is proposed using common spatial pattern (CSP) and convolutional neural network (CNN). Firstly, artificial preictal EEG signals based on the original ones are generated by combining the segmented pre-ictal signals to solve the trial imbalance problem between the two states. Secondly, a feature extractor employing wavelet packet decomposition and CSP is designed to extract the distinguishing features in both the time domain and the frequency domain. It can improve overall accuracy while reducing the training time. Finally, a shallow CNN is applied to discriminate between the pre-ictal state and the inter-ictal state. Our proposed solution is evaluated on 23 patients' data from Boston Children's Hospital-MIT scalp EEG dataset by employing a leave-one-out cross-validation, and it achieves a sensitivity of 92. 2% and false prediction rate of 0. 12/h. Experimental result demonstrates that the proposed approach outperforms most state-of-the-art methods.

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TIST Journal 2019 Journal Article

Comparison and Modelling of Country-level Microblog User and Activity in Cyber-physical-social Systems Using Weibo and Twitter Data

Po Yang
Jing Liu
Jun Qi
Yun Yang
Xulong Wang
Zhihan Lv

As the rapid growth of social media technologies continues, Cyber-Physical-Social System (CPSS) has been a hot topic in many industrial applications. The use of “microblogging” services, such as Twitter, has rapidly become an influential way to share information. While recent studies have revealed that understanding and modelling microblog user behaviour with massive users’ data in social media are keen to success of many practical applications in CPSS, a key challenge in literatures is that diversity of geography and cultures in social media technologies strongly affect user behaviour and activity. The motivation of this article is to understand differences and similarities between microblogging users from different countries using social media technologies, and to attempt to design a Country-Level Micro-Blog User (CLMB) behaviour and activity model for supporting CPSS applications. We proposed a CLMB model for analysing microblogging user behaviour and their activity across different countries in the CPSS applications. The model has considered three important characteristics of user behaviour in microblogging data, including content of microblogging messages, user emotion index, and user relationship network. We evaluated CLBM model under the collected microblog dataset from 16 countries with the largest number of representative and active users in the world. Experimental results show that (1) for some countries with small population and strong cohesiveness, users pay more attention to social functionalities of microblogging service; (2) for some countries containing mostly large loose social groups, users use microblogging services as a news dissemination platform; (3) users in countries whose social network structure exhibits reciprocity rather than hierarchy will use more linguistic elements to express happiness in microblogging services.

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JBHI Journal 2018 Journal Article

User Profiling in Elderly Healthcare Services in China: Scalper Detection

Cheng Xie
Hongming Cai
Yun Yang
Lihong Jiang
Po Yang

Driven by the automation technologies and health informatics of Industry 4. 0, hospitals in China have deployed a complete automation system/platform for healthcare services accessing. Without much more Internet knowledge, elderlies usually seek the third-party to assist them to get healthcare services from Web or APPs, it consequently results in an unexpected situation that scalpers could grab all healthcare services booking by unrighteous means in order to resell to elderlies for a much higher price. Moreover, it is hard for physicians to identify the scalpers due to the complexity, ad-hoc, and multiscenario nature of healthcare processes. In this paper, a novel method is proposed for the identification and creation of user groups of scalpers in mobile healthcare services. The approach utilizes and extends state of the art data analysis approaches in the event-logs of the mobile system to identify user groups. Based on the user groups, user profiles are extracted by identifying representative eventcases from hierarchical user-event clusters. A comprehensive evaluation is conducted in a selected test-set from the event-logs of a mobile healthcare APP. The result shows its accuracy and effectiveness in scalper detection in mobile healthcare APP. Further, a complete case study is deployed in a real word hospital to ensure its utility, efficacy, and reliability.

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