YNICL Journal 2024 Journal Article
Full kinetic modeling analysis of [18F]fluorocholine Positron Emission Tomography (PET) at initial diagnosis of high-grade glioma
- Sebastià Rubí
- Pedro Bibiloni
- Marina Villar
- Marta Brell
- Manuel Valiente
- Margalida Galmés
- María Toscano
- Gabriel Matheu
PURPOSE: F]F-CHO) in high-grade gliomas (HGG) through a full PET kinetic modeling approach. Secondarily, we aimed to explore the relationship between the PET uptake measures and the HGG molecular features. MATERIALS AND METHODS: F]F-CHO-PET quantitative parameters and relevant molecular biomarkers in HGG. RESULTS: (p = 0.025) and TBR (p = 0.001) than the unmethylated ones. CONCLUSION: F]F-CHO uptake rate and MGMT methylation is suggested but needs further confirmation.