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Mingkun Xu

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8 papers
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8

AAAI Conference 2026 Conference Paper

Biologically-Inspired Evolutionary Domain Symbiosis for Few-shot and Zero-shot Point Cloud Semantic Segmentation

  • Changshuo Wang
  • Zhijian Hu
  • Xiang Fang
  • Zai Yang Yu
  • Yibin Wu
  • Mingkun Xu
  • Yusong Wang
  • Xingyu Gao

Few-shot and zero-shot point cloud semantic segmentation aim to accurately segment novel categories using limited or no labeled samples, respectively. However, existing methods face significant challenges including domain shifts between support and query sets and the inability to handle both few-shot and zero-shot scenarios within a unified framework. To address these issues, we propose a biologically-inspired Evolutionary Domain Symbiosis Network EDS-Net for unified few-shot and zero-shot point cloud semantic segmentation. Specifically, inspired by natural symbiotic evolution, we propose a Symbiotic Evolution Module (SEM) that models co-adaptation between support and query features through self-correlation and cross-correlation mechanisms. Second, motivated by genetic crossover mechanisms, we introduce a Vision-Semantic Bridging Module (VSBM) that treats visual prototypes and semantic prototypes as two “parent” individuals, creating fused offspring prototypes through adaptive crossover operations and mutation strategies for zero-shot scenarios. Third, we develop a multi-generational evolutionary optimization framework employing an adaptive gating network to learn optimal fusion weights across different evolutionary stages. Extensive experiments demonstrate that EDS-Net with biological interpretability achieves state-of-the-art performance on both few-shot and zero-shot settings.

AAAI Conference 2026 Conference Paper

MMPG: MoE-based Adaptive Multi-Perspective Graph Fusion for Protein Representation Learning

  • Yusong Wang
  • Jialun Shen
  • Zhihao Wu
  • Yicheng Xu
  • Shiyin Tan
  • Mingkun Xu
  • Changshuo Wang
  • Zixing Song

Graph Neural Networks (GNNs) have been widely adopted for Protein Representation Learning (PRL), as residue interaction networks can be naturally represented as graphs. Current GNN-based PRL methods typically rely on single-perspective graph construction strategies, which capture partial properties of residue interactions, resulting in incomplete protein representations. To address this limitation, we propose MMPG, a framework that constructs protein graphs from multiple perspectives and adaptively fuses them via Mixture of Experts (MoE) for PRL. MMPG constructs graphs from physical, chemical, and geometric perspectives to characterize different properties of residue interactions. To capture both perspective-specific features and their synergies, we develop an MoE module, which dynamically routes perspectives to specialized experts, where experts learn intrinsic features and cross-perspective interactions. We quantitatively verify that MoE automatically specializes experts in modeling distinct levels of interaction—from individual representations, to pairwise inter-perspective synergies, and ultimately to a global consensus across all perspectives. Through integrating this multi-level information, MMPG produces superior protein representations and achieves advanced performance on four different downstream protein tasks.

AAAI Conference 2025 Conference Paper

BIG-FUSION: Brain-Inspired Global-Local Context Fusion Framework for Multimodal Emotion Recognition in Conversations

  • Yusong Wang
  • Xuanye Fang
  • Huifeng Yin
  • Dongyuan Li
  • Guoqi Li
  • Qi Xu
  • Yi Xu
  • Shuai Zhong

Considering the importance of capturing both global conversational topics and local speaker dependencies for multimodal emotion recognition in conversations, current approaches first utilize sequence models like Transformer to extract global context information, then apply Graph Neural Networks to model local speaker dependencies for local context information extraction, coupled with Graph Contrastive Learning (GCL) to enhance node representation learning. However, this sequential design introduces potential biases: the extracted global context information inevitably influences subsequent processing, compromising the independence and diversity of the original local features; current graph augmentation methods in GCL cannot consider both global and local context information in conversations to evaluate the node importance, hindering the learning of key information. Inspired by the human brain excels at handling complex tasks by efficiently integrating local and global information processing mechanisms, we propose an aligned global-local context fusion framework for sequence-based design to address these problems. This design includes a dual-attention Transformer and a dual-evaluation method for graph augmentation in GCL. The dual-attention Transformer combines global attention for overall context extraction with sliding-window attention for local context capture, both enhanced by spiking neuron dynamics. The dual-evaluation method in GCL comprises global importance evaluation to identify nodes crucial for overall conversation context, and local importance evaluation to detect nodes significant for local semantics, generating augmented graph views that preserve both global and local information. This approach ensures balanced information processing throughout the pipeline, enhancing biological plausibility and achieving superior emotion recognition.

ECAI Conference 2025 Conference Paper

CogniSNN: An Exploration to Random Graph Architecture Based Spiking Neural Networks with Enhanced Depth-Scalability and Path-Plasticity

  • Yongsheng Huang
  • Peibo Duan
  • Zhipeng Liu
  • Kai Sun
  • Changsheng Zhang 0001
  • Bin Zhang 0001
  • Mingkun Xu

Currently, most spiking neural networks (SNNs) still mimic the chain-like hierarchical architecture in traditional artificial neural networks (ANNs). This method significantly differs from random connections between neurons found in biological brains, limiting the ability to model the evolving mechanisms of neural pathways in biological neural systems, particularly in terms of dynamic depth-scalability and adaptive path-plasticity. This paper develops a new modeling paradigm for SNNs with random graph architecture (RGA), termed Cognition-aware SNN (CogniSNN). Furthermore, we model the depth-scalability and path-plasticity in CogniSNN by introducing a modified spiking residual neural node (ResNode) to counteract network degradation in deeper graph pathways, as well as a critical path-based algorithm that enables CogniSNN to perform path reusability on new tasks leveraging the features of the data and the RGA learned in old tasks. Experiments show that the performance of CogniSNN with redesigned ResNode is comparable, even superior, to current state-of-the-art SNNs on neuromorphic datasets. The critical path-based approach effectively achieves path reuse capability while maintaining expected performance in learning new tasks that are similar to or distinct from the old ones. This study showcases the potential of RGA-based SNNs and paves a new path for modeling the fusion of computational neuroscience and deep intelligent agents. The code is available at github. com/Yongsheng124/CogniSNN.

ICML Conference 2025 Conference Paper

Efficient ANN-SNN Conversion with Error Compensation Learning

  • Chang Liu 0030
  • Jiangrong Shen
  • Xuming Ran
  • Mingkun Xu
  • Qi Xu 0008
  • Yi Xu 0008
  • Gang Pan 0001

Artificial neural networks (ANNs) have demonstrated outstanding performance in numerous tasks, but deployment in resource-constrained environments remains a challenge due to their high computational and memory requirements. Spiking neural networks (SNNs) operate through discrete spike events and offer superior energy efficiency, providing a bio-inspired alternative. However, current ANN-to-SNN conversion often results in significant accuracy loss and increased inference time due to conversion errors such as clipping, quantization, and uneven activation. This paper proposes a novel ANN-to-SNN conversion framework based on error compensation learning. We introduce a learnable threshold clipping function, dual-threshold neurons, and an optimized membrane potential initialization strategy to mitigate the conversion error. Together, these techniques address the clipping error through adaptive thresholds, dynamically reduce the quantization error through dual-threshold neurons, and minimize the non-uniformity error by effectively managing the membrane potential. Experimental results on CIFAR-10, CIFAR-100, ImageNet datasets show that our method achieves high-precision and ultra-low latency among existing conversion methods. Using only two time steps, our method significantly reduces the inference time while maintains competitive accuracy of 94. 75% on CIFAR-10 dataset under ResNet-18 structure. This research promotes the practical application of SNNs on low-power hardware, making efficient real-time processing possible.

ICML Conference 2025 Conference Paper

Enhancing Graph Contrastive Learning for Protein Graphs from Perspective of Invariance

  • Yusong Wang 0003
  • Shiyin Tan
  • Jialun Shen
  • Yicheng Xu
  • Haobo Song
  • Qi Xu 0008
  • Prayag Tiwari
  • Mingkun Xu

Graph Contrastive Learning (GCL) improves Graph Neural Network (GNN)-based protein representation learning by enhancing its generalization and robustness. Existing GCL approaches for protein representation learning rely on 2D topology, where graph augmentation is solely based on topological features, ignoring the intrinsic biological properties of proteins. Besides, 3D structure-based protein graph augmentation remains unexplored, despite proteins inherently exhibiting 3D structures. To bridge this gap, we propose novel biology-aware graph augmentation strategies from the perspective of invariance and integrate them into the protein GCL framework. Specifically, we introduce Functional Community Invariance (FCI)-based graph augmentation, which employs spectral constraints to preserve topology-driven community structures while incorporating residue-level chemical similarity as edge weights to guide edge sampling and maintain functional communities. Furthermore, we propose 3D Protein Structure Invariance (3-PSI)-based graph augmentation, leveraging dihedral angle perturbations and secondary structure rotations to retain critical 3D structural information of proteins while diversifying graph views. Extensive experiments on four different protein-related tasks demonstrate the superiority of our proposed GCL protein representation learning framework.

AAAI Conference 2025 Conference Paper

Multi-View Incremental Learning with Structured Hebbian Plasticity for Enhanced Fusion Efficiency

  • Yuhong Chen
  • Ailin Song
  • Huifeng Yin
  • Shuai Zhong
  • Fuhai Chen
  • Qi Xu
  • Shiping Wang
  • Mingkun Xu

The rapid evolution of multimedia technology has revolutionized human perception, paving the way for multi-view learning. However, traditional multi-view learning approaches are tailored for scenarios with fixed data views, falling short of emulating the intricate cognitive procedures of the human brain processing signals sequentially. Our cerebral architecture seamlessly integrates sequential data through intricate feed-forward and feedback mechanisms. In stark contrast, traditional methods struggle to generalize effectively when confronted with data spanning diverse domains, highlighting the need for innovative strategies that can mimic the brain's adaptability and dynamic integration capabilities. In this paper, we propose a bio-neurologically inspired multi-view incremental framework named MVIL aimed at emulating the brain's fine-grained fusion of sequentially arriving views. MVIL lies two fundamental modules: structured Hebbian plasticity and synaptic partition learning. The structured Hebbian plasticity reshapes the structure of weights to express the high correlation between view representations, facilitating a fine-grained fusion of view representations. Moreover, synaptic partition learning is efficient in alleviating drastic changes in weights and also retaining old knowledge by inhibiting partial synapses. These modules bionically play a central role in reinforcing crucial associations between newly acquired information and existing knowledge repositories, thereby enhancing the network's capacity for generalization. Experimental results on six benchmark datasets show MVIL's effectiveness over state-of-the-art methods.

IJCAI Conference 2021 Conference Paper

Exploiting Spiking Dynamics with Spatial-temporal Feature Normalization in Graph Learning

  • Mingkun Xu
  • YuJie Wu
  • Lei Deng
  • Faqiang Liu
  • Guoqi Li
  • Jing Pei

Biological spiking neurons with intrinsic dynamics underlie the powerful representation and learning capabilities of the brain for processing multimodal information in complex environments. Despite recent tremendous progress in spiking neural networks (SNNs) for handling Euclidean-space tasks, it still remains challenging to exploit SNNs in processing non-Euclidean-space data represented by graph data, mainly due to the lack of effective modeling framework and useful training techniques. Here we present a general spike-based modeling framework that enables the direct training of SNNs for graph learning. Through spatial-temporal unfolding for spiking data flows of node features, we incorporate graph convolution filters into spiking dynamics and formalize a synergistic learning paradigm. Considering the unique features of spike representation and spiking dynamics, we propose a spatial-temporal feature normalization (STFN) technique suitable for SNN to accelerate convergence. We instantiate our methods into two spiking graph models, including graph convolution SNNs and graph attention SNNs, and validate their performance on three node-classification benchmarks, including Cora, Citeseer, and Pubmed. Our model can achieve comparable performance with the state-of-the-art graph neural network (GNN) models with much lower computation costs, demonstrating great benefits for the execution on neuromorphic hardware and prompting neuromorphic applications in graphical scenarios.

v2026.09.13