JBHI Journal 2025 Journal Article
CDAF-Net: A Contextual Contrast Detail Attention Feature Fusion Network for Low-Dose CT Denoising
- Yaoyao Ma
- Jing Wang
- Chao Xu
- Yuling Huang
- Minghang Chu
- Zhiwei Fan
- Yishen Xu
- Di Wu
Low-dose computed tomography (LDCT) is a specialized CT scan with a lower radiation dose than normal-dose CT. However, the reduced radiation dose can introduce noise and artifacts, affecting diagnostic accuracy. To enhance the LDCT image quality, we propose a Contextual Contrast Detail Attention Feature Fusion Network (CDAF-Net) for LDCT denoising. Firstly, the LDCT image, with dimensions 1 × H × W, is mapped to a feature map with dimensions C × H × W, and it is processed through the Contextual Contrast Detail Attention (CCDA) module and the Selective Kernel Feature Fusion (SKFF) module. The CCDA module combines a global contextual attention mechanism with detail-enhanced differential convolutions to better understand the overall semantics and structure of the LDCT image, capturing subtle changes and details. The SKFF module effectively merges shallow features extracted by the encoder with deep features from the decoder, integrating feature representations from different levels. This process is repeated across four different resolution feature maps, and the denoised LDCT image is output through a skip connection. We conduct experiments on the Mayo dataset, the LDCT-and-Projection-Data dataset, and the Piglet dataset. Specifically, the CDAF-Net achieves the optimal metrics with a PSNR of 33. 7262 dB, an SSIM of 0. 9254, and an RMSE of 5. 3731 on the Mayo dataset. Improvements are also observed in head CT and ultra-low-dose chest CT images of the LDCT-and-Projection-Data dataset and the Piglet dataset. Experimental results show that the proposed CDAF-Net algorithm provides superior denoising performance compared with the state-of-the-art (SOTA) algorithms.