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Mi Wang

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3 papers
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3

AAAI Conference 2026 Conference Paper

CHARM: Collaborative Harmonization Across Arbitrary Modalities for Modality-Agnostic Semantic Segmentation

  • Lekang Wen
  • Jing Xiao
  • Liang Liao
  • Jiajun Chen
  • Mi Wang

Modality-agnostic Semantic Segmentation (MaSS) aims to achieve robust scene understanding across arbitrary combinations of input modality. Existing methods typically rely on explicit feature alignment to achieve modal homogenization, which dilutes the distinctive strengths of each modality and destroys their inherent complementarity. To achieve cooperative harmonization rather than homogenization, we propose CHARM, a novel complementary learning framework designed to implicitly align content while preserving modality-specific advantages through two components: (1) Mutual Perception Unit (MPU), enabling implicit alignment through window-based cross-modal interaction, where modalities serve as both queries and contexts for each other to discover modality-interactive correspondences; (2) A dual-path optimization strategy that decouples training into Collaborative Learning Strategy (CoL) for complementary fusion learning and Individual Enhancement Strategy (InE) for protected modality-specific optimization. Experiments across multiple datasets and backbones indicate that CHARM consistently outperform the baselines, with significant increment on the fragile modalities. This work shifts the focus from model homogenization to harmonization, enabling cross-modal complementarity for true harmony in diversity.

YNIMG Journal 2025 Journal Article

Altered brain network dynamics during rumination in remitted depression

  • Su Shu
  • Wenwen Ou
  • Mohan Ma
  • Hairuo He
  • Qianqian Zhang
  • Mei Huang
  • Wentao Chen
  • Aoqian Deng

Rumination is a known risk factor for depression relapse. Understanding its neurobiological mechanisms during depression remission can inform strategies to prevent relapse, yet the temporal dynamics of brain networks during rumination in remitted depression remain unclear. Here, we collected rumination induction fMRI data from 42 patients with remitted depression and 41 healthy controls (HCs). Using an energy landscape approach, we investigated the temporal dynamics of brain networks during rumination. The appearance frequency (AF) and transition frequency (TF) metrics were defined to quantify the dynamic properties of brain states. Patients during remission showed higher levels of rumination than HCs. Both groups exhibited four brain states during rumination, which consisted of complementary network group activation (states 1 and 2, states 3 and 4). In patients, the AFs of and reciprocal TFs between states 1 and 2 during rumination were significantly increased, while AFs of states 3 and 4 and reciprocal TFs involving states 1-3, 1-4, 2-3, and 2-4 were decreased, both when compared to HCs and relative to patients themselves during distraction. Moreover, we found that for patients, the AF of state 1 was negatively correlated with rumination levels and marginally positively associated with attention, while the AF of state 2 was negatively associated with performance on attention tasks. Our study revealed altered dynamic characteristics of brain states composed of network groups during rumination in remitted depression. Additionally, the findings suggest that heightened self-focus linked to rumination may impair the brain's ability to efficiently allocate attentional resources.

YNICL Journal 2025 Journal Article

Brain network dynamics during rumination relate to relapse of depression

  • Su Shu
  • Yumeng Ju
  • Mi Wang
  • Wenwen Ou
  • Mohan Ma
  • Qianqian Zhang
  • Mei Huang
  • Hairuo He

BACKGROUND: Rumination is a maladaptive cognitive style and a risk factor for relapse of depression. However, the clinically relevant pattern of dynamic network reconfiguration during rumination in remitted depression and its implication in relapse remained unclear. METHODS: We employed a rumination induction neuroimaging paradigm in which subjects would be guided into an active rumination state and a distraction state. Forty-two patients with remitted depression were involved. Participants underwent assessments of rumination behavior and imaging tasks, and were then monitored for two year to assess the potential relapse of depression. A time-resolved community detection approach was applied to investigate the temporal dynamics of brain networks, and the dynamic network properties including flexibility and integration were analyzed. RESULTS: = 0.036). Moreover, elastic net regression indicated that dynamic network features could predict two-year relapse outcomes with moderate accuracy (AUC = 0.70). CONCLUSIONS: Our findings reveal a potential mechanistic link between the brain network dynamics during rumination and relapse of depression, shedding light on the intricate relationship between cognitive-affective processes, neural dynamics, and the potential vulnerability to depression recurrence.

v2026.09.13