Author name cluster

Le Xue

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4 papers

2 author rows

AAAI Conference 2026 Conference Paper

PET2Rep: Towards Vision-Language Model-Drived Automated Radiology Report Generation for Positron Emission Tomography

Yichi Zhang
Wenbo Zhang
Zehui Ling
Gang Feng
Sisi Peng
Deshu Chen
Yuchen Liu
Hongwei Zhang

Positron emission tomography (PET) is a cornerstone of modern oncologic and neurologic imaging, distinguished by its unique ability to illuminate dynamic metabolic processes that transcend the anatomical focus of traditional imaging technologies. Radiology reports are essential for clinical decision making, yet their manual creation is labor-intensive and time-consuming. Recent advancements of vision-language models (VLMs) have shown strong potential in medical applications, presenting a promising avenue for automating report generation. However, existing applications of VLMs in the medical domain have predominantly focused on structural imaging modalities, while the unique characteristics of molecular PET imaging have largely been overlooked. To bridge the gap, we introduce PET2Rep, a large-scale comprehensive benchmark for evaluation of general and medical VLMs for radiology report generation for PET images. PET2Rep stands out as the first dedicated dataset for PET report generation with metabolic information, uniquely capturing whole-body image-report pairs that cover dozens of organs to fill the critical gap in existing benchmarks and mirror real-world clinical comprehensiveness. In addition to widely recognized natural language generation metrics, we introduce a series of clinical efficiency metrics to evaluate the quality of radiotracer uptake pattern description in key organs in generated reports. We conduct a head-to-head comparison of 30 cutting-edge general-purpose and medical-specialized VLMs. The results show that the current state-of-the-art VLMs perform poorly on PET report generation task, falling considerably short of fulfilling practical needs. Moreover, we identify several key insufficiency that need to be addressed to advance the development in medical applications. We believe PET2Rep will serve as a platform for the development and application of VLMs for PET imaging, accelerating the development of trustworthy reporting tools that can genuinely alleviate radiologist burden and enhance patient care.

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ICRA Conference 2024 Conference Paper

Hierarchical Point Attention for Indoor 3D Object Detection

Manli Shu
Le Xue
Ning Yu 0006
Roberto Martín-Martín
Caiming Xiong
Tom Goldstein
Juan Carlos Niebles
Ran Xu 0001

3D object detection is an essential vision technique for various robotic systems, such as augmented reality and domestic robots. Transformers as versatile network architectures have recently seen great success in 3D point cloud object detection. However, the lack of hierarchy in a plain transformer restrains its ability to learn features at different scales. Such limitation makes transformer detectors perform worse on smaller objects and affects their reliability in indoor environments where small objects are the majority. This work proposes two novel attention operations as generic hierarchical designs for point-based transformer detectors. First, we propose Aggregated Multi-Scale Attention (MS-A) that builds multi-scale tokens from a single-scale input feature to enable more fine-grained feature learning. Second, we propose Size-Adaptive Local Attention (Local-A) with adaptive attention regions for localized feature aggregation within bounding box proposals. Both attention operations are model-agnostic network modules that can be plugged into existing point cloud transformers for end-to-end training. We evaluate our method on two widely used indoor detection benchmarks. By plugging our proposed modules into the state-of-the-art transformer-based 3D detectors, we improve the previous best results on both benchmarks, with more significant improvements on smaller objects.

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NeurIPS Conference 2024 Conference Paper

MINT-1T: Scaling Open-Source Multimodal Data by 10x: A Multimodal Dataset with One Trillion Tokens

Anas Awadalla
Le Xue
Oscar Lo
Manli Shu
Hannah Lee
Etash Guha
Matt Jordan
Sheng Shen

Multimodal interleaved datasets featuring free-form interleaved sequences of images and text are crucial for training frontier large multimodal models (LMMs). Despite the rapid progression of open-source LMMs, there remains a pronounced scarcity of large-scale, open-source multimodal interleaved datasets. In response, we introduce MINT-1T, the most extensive and diverse open-source Multimodal INTerleaved dataset to date. MINT-1T comprises of one trillion text tokens and 3. 4 billion images, a 10x scale-up from existing open-source datasets. Additionally, we include previously untapped sources such as PDFs and ArXiv papers. As scaling multimodal interleaved datasets requires substantial engineering effort, sharing the data curation process and releasing the dataset greatly benefits the community. Our experiments show that LMMs trained on MINT-1T rival the performance of models trained on the previous leading dataset, OBELICS. We release our data at https: //github. com/mlfoundations/MINT-1T.

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ICLR Conference 2024 Conference Paper

Retroformer: Retrospective Large Language Agents with Policy Gradient Optimization

Weiran Yao
Shelby Heinecke
Juan Carlos Niebles
Zhiwei Liu 0001
Yihao Feng
Le Xue
Rithesh R. N.
Zeyuan Chen 0001

Recent months have seen the emergence of a powerful new trend in which large language models (LLMs) are augmented to become autonomous language agents capable of performing objective oriented multi-step tasks on their own, rather than merely responding to queries from human users. Most existing language agents, however, are not optimized using environment-specific rewards. Although some agents enable iterative refinement through verbal feedback, they do not reason and plan in ways that are compatible with gradient-based learning from rewards. This paper introduces a principled framework for reinforcing large language agents by learning a retrospective model, which automatically tunes the language agent prompts from environment feedback through policy gradient. Specifically, our proposed agent architecture learns from rewards across multiple environments and tasks, for fine-tuning a pre-trained language model which refines the language agent prompt by summarizing the root cause of prior failed attempts and proposing action plans. Experimental results on various tasks demonstrate that the language agents improve over time and that our approach considerably outperforms baselines that do not properly leverage gradients from the environment.

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