Author name cluster

Lang Qin

Possible papers associated with this exact author name in Arrow. This page groups case-insensitive exact name matches and is not a full identity disambiguation profile.

7 papers

1 author row

AAAI Conference 2025 Conference Paper

GRSN: Gated Recurrent Spiking Neurons for POMDPs and MARL

Lang Qin
Ziming Wang
Runhao Jiang
Rui Yan
Huajin Tang

Spiking neural networks (SNNs) are widely applied in various fields due to their energy-efficient and fast-inference capabilities. Applying SNNs to reinforcement learning (RL) can significantly reduce the computational resource requirements for agents and improve the algorithm's performance under resource-constrained conditions. However, in current spiking reinforcement learning (SRL) algorithms, the simulation results of multiple time steps can only correspond to a single-step decision in RL. This is quite different from the real temporal dynamics in the brain and also fails to fully exploit the capacity of SNNs to process temporal data. In order to address this temporal mismatch issue and further take advantage of the inherent temporal dynamics of spiking neurons, we propose a novel temporal alignment paradigm (TAP) that leverages the single-step update of spiking neurons to accumulate historical state information in RL and introduces gated units to enhance the memory capacity of spiking neurons. Experimental results show that our method can solve partially observable Markov decision processes (POMDPs) and multi-agent cooperation problems with similar performance as recurrent neural networks (RNNs) but with about 50\% power consumption.

PDF Details DOI

JBHI Journal 2024 Journal Article

Predicting ICU Interventions: A Transparent Decision Support Model Based on Multivariate Time Series Graph Convolutional Neural Network

Zhen Xu
Jinjin Guo
Lang Qin
Yuntao Xie
Yao Xiao
Xinran Lin
Qiming Li
Xinyang Li

In this study, we present a novel approach for predicting interventions for patients in the intensive care unit using a multivariate time series graph convolutional neural network. Our method addresses two critical challenges: the need for timely and accurate decisions based on changing physiological signals, drug administration information, and static characteristics; and the need for interpretability in the decision-making process. Drawing on real-world ICU records from the MIMIC-III dataset, we demonstrate that our approach significantly improves upon existing machine learning and deep learning methods for predicting two targeted interventions, mechanical ventilation and vasopressors. Our model achieved an accuracy improvement from 81. 6% to 91. 9% and a F1 score improvement from 0. 524 to 0. 606 for predicting mechanical ventilation interventions. For predicting vasopressor interventions, our model achieved an accuracy improvement from 76. 3% to 82. 7% and a F1 score improvement from 0. 509 to 0. 619. We also assessed the interpretability by performing an adjacency matrix importance analysis, which revealed that our model uses clinically meaningful and appropriate features for prediction. This critical aspect can help clinicians gain insights into the underlying mechanisms of interventions, allowing them to make more informed and precise clinical decisions. Overall, our study represents a significant step forward in the development of decision support systems for ICU patient care, providing a powerful tool for improving clinical outcomes and enhancing patient safety.

Details DOI

YNIMG Journal 2024 Journal Article

Wireless optically pumped magnetometer MEG

Hao Cheng
Kaiyan He
Congcong Li
Xiao Ma
Fufu Zheng
Wei Xu
Pan Liao
Rui Yang

The current magnetoencephalography (MEG) systems, which rely on cables for control and signal transmission, do not fully realize the potential of wearable optically pumped magnetometers (OPM). This study presents a significant advancement in wireless OPM-MEG by reducing magnetization in the electronics and developing a tailored wireless communication protocol. Our protocol effectively eliminates electromagnetic interference, particularly in the critical frequency bands of MEG signals, and accurately synchronizes the acquisition and stimulation channels with the host computer's clock. We have successfully achieved single-channel wireless OPM-MEG measurement and demonstrated its reliability by replicating three well-established experiments: The alpha rhythm, auditory evoked field, and steady-state visual evoked field in the human brain. Our prototype wireless OPM-MEG system not only streamlines the measurement process but also represents a major step forward in the development of wearable OPM-MEG applications in both neuroscience and clinical research.

Details DOI

IJCAI Conference 2023 Conference Paper

A Low Latency Adaptive Coding Spike Framework for Deep Reinforcement Learning

Lang Qin
Rui Yan
Huajin Tang

In recent years, spiking neural networks (SNNs) have been used in reinforcement learning (RL) due to their low power consumption and event-driven features. However, spiking reinforcement learning (SRL), which suffers from fixed coding methods, still faces the problems of high latency and poor versatility. In this paper, we use learnable matrix multiplication to encode and decode spikes, improving the flexibility of the coders and thus reducing latency. Meanwhile, we train the SNNs using the direct training method and use two different structures for online and offline RL algorithms, which gives our model a wider range of applications. Extensive experiments have revealed that our method achieves optimal performance with ultra-low latency (as low as 0. 8% of other SRL methods) and excellent energy efficiency (up to 5X the DNNs) in different algorithms and different environments.

PDF Details DOI

YNIMG Journal 2023 Journal Article

State-dependent and region-specific alterations of cerebellar connectivity across stable human wakefulness and NREM sleep states

Jiayi Liu
Guangyuan Zou
Jing Xu
Shuqin Zhou
Lang Qin
Hongqiang Sun
Qihong Zou
Jia-Hong Gao

Sleep regulation and functioning may rely on systematic coordination throughout the whole brain, including the cerebellum. However, whether and how interactions between the cerebellum and other brain regions vary across sleep stages remain poorly understood. Here, using simultaneous EEG-fMRI recordings captured from 73 participants during wakefulness and non-rapid eye movement (NREM) sleep, we constructed cerebellar connectivity among intrinsic functional networks with intra-cerebellar, neocortical and subcortical regions. We uncovered that cerebellar connectivity exhibited sleep-dependent alterations: slight differences between wakefulness and N1/N2 sleep and greater changes in N3 sleep than other states. Region-specific cerebellar connectivity changes between N2 sleep and N3 sleep were also revealed: general breakdown of intra-cerebellar connectivity, enhancement of limbic-cerebellar connectivity and alterations of cerebellar connectivity with spatially specific neocortices. Further correlation analysis showed that functional connectivity between the cerebellar Control II network and regions (including the insula, hippocampus, and amygdala) correlated with delta power during N3 and beta power during N2 sleep. These findings systematically reveal altered cerebellar connectivity among intrinsic networks from wakefulness to deep sleep and highlight the potential role of the cerebellum in sleep regulation and functioning.

Details DOI

YNIMG Journal 2022 Journal Article

Disrupted neural tracking of sound localization during non-rapid eye movement sleep

Yan Wang
Lingxi Lu
Guangyuan Zou
Li Zheng
Lang Qin
Qihong Zou
Jia-Hong Gao

Spatial hearing in humans is a high-level auditory process that is crucial to rapid sound localization in the environment. Both neurophysiological models with animals and neuroimaging evidence from human subjects in the wakefulness stage suggest that the localization of auditory objects is mainly located in the posterior auditory cortex. However, whether this cognitive process is preserved during sleep remains unclear. To fill this research gap, we investigated the sleeping brain's capacity to identify sound locations by recording simultaneous electroencephalographic (EEG) and magnetoencephalographic (MEG) signals during wakefulness and non-rapid eye movement (NREM) sleep in human subjects. Using the frequency-tagging paradigm, the subjects were presented with a basic syllable sequence at 5 Hz and a location change that occurred every three syllables, resulting in a sound localization shift at 1.67 Hz. The EEG and MEG signals were used for sleep scoring and neural tracking analyses, respectively. Neural tracking responses at 5 Hz reflecting basic auditory processing were observed during both wakefulness and NREM sleep, although the responses during sleep were weaker than those during wakefulness. Cortical responses at 1.67 Hz, which correspond to the sound location change, were observed during wakefulness regardless of attention to the stimuli but vanished during NREM sleep. These results for the first time indicate that sleep preserves basic auditory processing but disrupts the higher-order brain function of sound localization.

Details DOI

YNIMG Journal 2022 Journal Article

Informed MEG/EEG source imaging reveals the locations of interictal spikes missed by SEEG

Su Shu
Shen Luo
Miao Cao
Ke Xu
Lang Qin
Li Zheng
Jing Xu
Xiongfei Wang

Determining the accurate locations of interictal spikes has been fundamental in the presurgical evaluation of epilepsy surgery. Stereo-electroencephalography (SEEG) is able to directly record cortical activity and localize interictal spikes. However, the main caveat of SEEG techniques is that they have limited spatial sampling (covering <5% of the whole brain), which may lead to missed spikes originating from brain regions that were not covered by SEEG. To address this problem, we propose a SEEG-informed minimum-norm estimates (SIMNE) method by combining SEEG with magnetoencephalography (MEG) or EEG. Specifically, the spike locations determined by SEEG offer as a priori information to guide MEG source reconstruction. Both computer simulations and experiments using data from five epilepsy patients were conducted to evaluate the performance of SIMNE. Our results demonstrate that SIMNE generates more accurate source estimation than a traditional minimum-norm estimates method and reveals the locations of spikes missed by SEEG, which would improve presurgical evaluation of the epileptogenic zone.

Details DOI