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Ke Peng

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3 papers
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3

EAAI Journal 2026 Journal Article

Global-to-Local Deep Interaction and Boundary-Aware Transformer for accurate polyp segmentation

  • Xiaojuan Liu
  • Xuan Li
  • Zhi Liu
  • Ke Peng
  • Shanxiong Chen
  • Yijue Zhang
  • Bo Hou

Colorectal cancer is a highly preventable disease. Colonoscopy allows for the detection and removal of polyps, which enables early diagnosis and timely intervention. In clinical practice, automatic polyp segmentation techniques based on colonoscopy images can improve both detection efficiency and accuracy, while helping physicians accurately locate polyps. However, existing methods still have limitations in coordinating global and local features, fusing multi-scale features, and handling ambiguous boundaries. To address these challenges, this paper proposes the Global-to-Local Deep Interaction and Boundary-Aware Transformer. This approach incorporates a Global–Local Aggregation module to coordinate fine-grained details with semantic information; employs a Multi-Scale Residual Decoder to enhance cross-layer feature fusion efficiency; and introduces a Dynamic Feature Fusion Module comprising Hierarchical Fusion and Error-Aware Refinement, for adaptive optimisation in boundary regions. We conducted extensive experiments and comparative analyses on five publicly available polyp datasets, evaluating our model against 15 state-of-the-art approaches. To further validate the model’s generalisation capabilities, we also designed experiments targeting small polyps. The experimental results show that our method performs well across multiple datasets, especially with mean Dice scores of 93. 9% on CVC-ClinicDB and 84. 7% on ETIS-LaribPolypDB.

YNICL Journal 2021 Journal Article

Hemodynamic changes associated with common EEG patterns in critically ill patients: Pilot results from continuous EEG-fNIRS study

  • Ali Kassab
  • Dènahin Hinnoutondji Toffa
  • Manon Robert
  • Frédéric Lesage
  • Ke Peng
  • Dang Khoa Nguyen

Functional near-infrared spectroscopy (fNIRS) is currently the only non-invasive method allowing for continuous long-term assessment of cerebral hemodynamic. We evaluate the feasibility of using continueous electroencephalgraphy (cEEG)-fNIRS to study the cortical hemodynamic associated with status epilepticus (SE), burst suppression (BS) and periodic discharges (PDs). Eleven adult comatose patients admitted to the neuroICU for SE were recruited, and cEEG-fNIRS monitoring was performed to measure concentration changes in oxygenated (HbO) and deoxygenated hemoglobin (HbR). Seizures were associated with a large increase HbO and a decrease in HbR whose durations were positively correlated with the seizures' length. Similar observations were made for hemodynamic changes associated with bursts, showing overall increases in HbO and decreases in HbR relative to the suppression periods. PDs were seen to induce widespread HbO increases and HbR decreases. These results suggest that normal neurovascular coupling is partially retained with the hemodynamic response to the detected EEG patterns in these patients. However, the shape and distribution of the response were highly variable. This work highlighted the feasibility of conducting long-term cEEG-fNIRS to monitor hemodynamic changes over a large cortical area in critically ill patients, opening new routes for better understanding and management of abnormal EEG patterns in neuroICU.

YNIMG Journal 2016 Journal Article

Using patient-specific hemodynamic response function in epileptic spike analysis of human epilepsy: a study based on EEG–fNIRS

  • Ke Peng
  • Dang Khoa Nguyen
  • Phetsamone Vannasing
  • Julie Tremblay
  • Frédéric Lesage
  • Philippe Pouliot

Functional near-infrared spectroscopy (fNIRS) can be combined with electroencephalography (EEG) to continuously monitor the hemodynamic signal evoked by epileptic events such as seizures or interictal epileptiform discharges (IEDs, aka spikes). As estimation methods assuming a canonical shape of the hemodynamic response function (HRF) might not be optimal, we sought to model patient-specific HRF (sHRF) with a simple deconvolution approach for IED-related analysis with EEG–fNIRS data. Furthermore, a quadratic term was added to the model to account for the nonlinearity in the response when IEDs are frequent. Prior to analyzing clinical data, simulations were carried out to show that the HRF was estimable by the proposed deconvolution methods under proper conditions. EEG–fNIRS data of five patients with refractory focal epilepsy were selected due to the presence of frequent clear IEDs and their unambiguous focus localization. For each patient, both the linear sHRF and the nonlinear sHRF were estimated at each channel. Variability of the estimated sHRFs was seen across brain regions and different patients. Compared with the SPM8 canonical HRF (cHRF), including these sHRFs in the general linear model (GLM) analysis led to hemoglobin activations with higher statistical scores as well as larger spatial extents on all five patients. In particular, for patients with frequent IEDs, nonlinear sHRFs were seen to provide higher sensitivity in activation detection than linear sHRFs. These observations support using sHRFs in the analysis of IEDs with EEG–fNIRS data.

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