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Jose M. Peña

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AAAI Conference 2022 Conference Paper

Personalized Public Policy Analysis in Social Sciences Using Causal-Graphical Normalizing Flows

  • Sourabh Balgi
  • Jose M. Peña
  • Adel Daoud

Structural Equation/Causal Models (SEMs/SCMs) are widely used in epidemiology and social sciences to identify and analyze the average causal effect (ACE) and conditional ACE (CACE). Traditional causal effect estimation methods such as Inverse Probability Weighting (IPW) and more recently Regression-With-Residuals (RWR) are widely used - as they avoid the challenging task of identifying the SCM parameters - to estimate ACE and CACE. However, much work remains before traditional estimation methods can be used for counterfactual inference, and for the benefit of Personalized Public Policy Analysis (P3A) in the social sciences. While doctors rely on personalized medicine to tailor treatments to patients in laboratory settings (relatively closed systems), P3A draws inspiration from such tailoring but adapts it for open social systems. In this article, we develop a method for counterfactual inference that we name causal-Graphical Normalizing Flow (c-GNF), facilitating P3A. A major advantage of c-GNF is that it suits the open system in which P3A is conducted. First, we show how c-GNF captures the underlying SCM without making any assumption about functional forms. This capturing capability is enabled by the deep neural networks that model the underlying SCM via observational data likelihood maximization using gradient descent. Second, we propose a novel dequantization trick to deal with discrete variables, which is a limitation of normalizing flows in general. Third, we demonstrate in experiments that c-GNF performs on-par with IPW and RWR in terms of bias and variance for estimating the ACE, when the true functional forms are known, and better when they are unknown. Fourth and most importantly, we conduct counterfactual inference with c-GNFs, demonstrating promising empirical performance. Because IPW and RWR, like other traditional methods, lack the capability of counterfactual inference, c-GNFs will likely play a major role in tailoring personalized treatment, facilitating P3A, optimizing social interventions - in contrast to the current ‘one-size-fits-all’ approach of existing methods.

JMLR Journal 2009 Journal Article

An Algorithm for Reading Dependencies from the Minimal Undirected Independence Map of a Graphoid that Satisfies Weak Transitivity

  • Jose M. Peña
  • Roland Nilsson
  • Johan Björkegren
  • Jesper Tegnér

We present a sound and complete graphical criterion for reading dependencies from the minimal undirected independence map G of a graphoid M that satisfies weak transitivity. Here, complete means that it is able to read all the dependencies in M that can be derived by applying the graphoid properties and weak transitivity to the dependencies used in the construction of G and the independencies obtained from G by vertex separation. We argue that assuming weak transitivity is not too restrictive. As an intermediate step in the derivation of the graphical criterion, we prove that for any undirected graph G there exists a strictly positive discrete probability distribution with the prescribed sample spaces that is faithful to G. We also report an algorithm that implements the graphical criterion and whose running time is considered to be at most O ( n 2 ( e + n )) for n nodes and e edges. Finally, we illustrate how the graphical criterion can be used within bioinformatics to identify biologically meaningful gene dependencies. [abs] [ pdf ][ bib ] &copy JMLR 2009. ( edit, beta )

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