YNICL Journal 2018 Journal Article
Quantitative analysis of neurite orientation dispersion and density imaging in grading gliomas and detecting IDH-1 gene mutation status
- Jing Zhao
- Ji-bin Li
- Jing-yan Wang
- Yu-liang Wang
- Da-wei Liu
- Xin-bei Li
- Yu-kun Song
- Yi-su Tian
Background and purpose: ) mutation status. Methods: Forty-two patients (male: 23, female: 19, mean age: 44.5 y) were recruited and underwent whole brain NODDI examination. Intracellular volume fraction (icvf) and orientation dispersion index (ODI) maps were derived. Three ROIs were manually placed on TP and PT regions for each case. The corresponding average values of icvf and ODI were calculated, and their diagnostic efficiency was assessed. Results: mutation status. Conclusions: mutation status has not been fully explored, as a larger sample size may be necessary to uncover benefits.