JBHI Journal 2026 Journal Article
A 6G-Enabled Hierarchical Contrastive Learning Framework for Multi-Scale Medical Time Series Analysis
- Le Sun
- Jie Lin
- Zhiguo Qu
- Yimin Yu
- Jinliang Liu
- Deepak Gupta
- Yanchun Zhang
Medical time series analysis, particularly for electrocardiogram (ECG) and electroencephalogram (EEG) signals, is essential in modern diagnostics, supporting early detection of conditions such as arrhythmias and epileptic seizures. However, existing approaches often struggle to capture multi-scale periodic patterns and longrange dependencies while meeting real-time processing demands. The envisioned 6G networks, with their terahertz communication and integrated sensing and communication (ISAC) capabilities, will generate vast volumes of high-fidelity physiological data at the network edge. This paradigm shift intensifies the conflict between the computational complexity of advanced AI models and the limited resources of edge devices, creating a critical bottleneck for deploying sophisticated analytics in real-world healthcare scenarios. To overcome these limitations, this paper introduces a 6G-enabled hierarchical contrastive learning framework, referred to as Hierarchical Contrastive Learning for Multi-Scale Medical time series analysis (HCL-MSM), which integrates three core components: a signal-adaptive encoder based on multi-period decomposition and 2D convolution, a patient-level contrastive module enhanced with decomposable multi-scale mixing, and a 6G-edge deployment module optimized via quantization and pruning. The framework effectively models nested physiological rhythms and cross-time dependencies in medical data, while maintaining low-latency operation under resource-constrained edge environments. We evaluated HCL-MSM on multiple clinical datasets under simulated 6G settings. Our framework achieves significant gains in arrhythmia detection, seizure prediction, and neurological monitoring. We evaluated HCL-MSM on multiple clinical datasets under simulated 6G settings. Our framework achieves significant gains in arrhythmia detection (F1-score: 86. 39 percent), seizure prediction (Recall: 87. 72 percent), and neurological monitoring (Recall: 87. 8 percent), outperforming existing state-of- the-art methods.