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Jiahong Dong

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AIIM Journal 2025 Journal Article

Medical multimodal foundation models in clinical diagnosis and treatment: Applications, challenges, and future directions

  • Kai Sun
  • Siyan Xue
  • Fuchun Sun
  • Haoran Sun
  • Yu Luo
  • Ling Wang
  • Siyuan Wang
  • Na Guo

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus driving the pursuit of precision medicine. The growing availability of multi-organ and multimodal datasets has accelerated the development of large-scale Medical Multimodal Foundation Models (MMFMs). These models, known for their strong generalization capabilities and rich representational power, are increasingly being adapted to address a wide range of clinical tasks, from early diagnosis to personalized treatment strategies. This review offers a comprehensive analysis of recent developments in MMFMs, focusing on three key aspects: datasets, model architectures, and clinical applications. We also explore the challenges and opportunities in optimizing multimodal representations and discuss how these advancements are shaping the future of healthcare by enabling improved patient outcomes and more efficient clinical workflows.

ICRA Conference 2025 Conference Paper

Multi-Segment Soft Robot Control Via Deep Koopman-Based Model Predictive Control

  • Lei Lv
  • Lei Liu 0076
  • Lei Bao
  • Fuchun Sun 0001
  • Jiahong Dong
  • Jianwei Zhang 0001
  • Xuemei Shan
  • Kai Sun

Soft robots, compared to regular rigid robots, as their multiple segments with soft materials bring flexibility and compliance, have the advantages of safe interaction and dexterous operation in the environment. However, due to its characteristics of high dimensional, nonlinearity, time-varying nature, and infinite degree of freedom, it has been challenges in achieving precise and dynamic control such as trajectory tracking and position reaching. To address these challenges, we propose a framework of Deep Koopman-based Model Predictive Control (DK-MPC) for handling multi-segment soft robots. We first employ a deep learning approach with sampling data to approximate the Koopman operator, which therefore linearizes the high-dimensional nonlinear dynamics of the soft robots into a finite-dimensional linear representation. Secondly, this linearized model is utilized within a model predictive control framework to compute optimal control inputs that minimize the tracking error between the desired and actual state trajectories. The real-world experiments on the soft robot “Chordata” demonstrate that DK-MPC could achieve highprecision control, showing the potential of DK-MPC for future applications to soft robots. More visualization results can be found at https://pinkmoon-io.github.io/DKMPC/.

v2026.09.13