YNICL Journal 2016 Journal Article
Combined 18F-FDG-PET and diffusion tensor imaging in mesial temporal lobe epilepsy with hippocampal sclerosis
- Javier Aparicio
- Mar Carreño
- Núria Bargalló
- Xavier Setoain
- Sebastià Rubí
- Jordi Rumià
- Carles Falcón
- Anna Calvo
OBJECTIVES: F-FDG-PET hypometabolism is related to DTI abnormalities. METHODS: F-FDG-PET. RESULTS: F-FDG-PET patterns: hypometabolism restricted to the anterior third (n = 7), hypometabolism extending to the middle third (n = 7), and hypometabolism extending to the posterior third (n = 7). Patients with anterior temporal hypometabolism showed DTI abnormalities in anterior association and commissural tracts while patients with posterior hypometabolism showed WM alterations in anterior and posterior tracts. CONCLUSIONS: F-FDG-PET hypometabolism along the epileptogenic temporal lobe. These findings suggest a variable network involvement among patients with MTLE-HS.