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Hongyi Wang

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17 papers
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17

EAAI Journal 2026 Journal Article

A deep learning-based imaging classification framework for interstitial lung disease

  • Hongyi Wang
  • Anqi Liu
  • Xiaoyan Yang
  • Yifei Ni
  • Jianping Wang
  • Jie Du
  • Yuhui Qiang
  • Bingbing Xie

Rationale Interstitial lung diseases (ILD) are a diverse group of conditions, often diagnosed using high-resolution chest computed tomography (HRCT), which is susceptible to subjective biases in interpretation. Objectives This study aims to develop and validate SPAIDNet (Spatial Pattern Analysis for ILD Diagnosis using a residual neural Network), a deep learning (DL) model for the automated classification of ILD, to reduce subjective biases and improve diagnostic consistency. Methods The study included 2901 ILD patients who underwent 5213 HRCT scans across multiple centers between July 2017 and June 2023. SPAIDNet, built upon the pre-trained residual neural network with 18 layers, utilizes multi-instance learning in three centers in China. Measurements and main results The model demonstrated exceptional performance, achieving macro-average area under the receiver operating characteristic curve (AUC) of over 0. 999 in internal validation, 0. 905 in external cohort I, and 0. 870 in external cohort II for multiclass classification. SPAIDNet outperformed both a junior radiologist (AUC: 0. 737) and a senior radiologist (AUC: 0. 763). Furthermore, DL-assisted the two radiologists saw significant improvements in diagnostic accuracy, with AUCs rising to 0. 817 and 0. 787, respectively. Conclusions These results underscore SPAIDNet's potential to offer high accuracy, robustness, and generalizability in ILD diagnosis, providing a valuable tool to mitigate the subjectivity inherent in HRCT image interpretation.

AAAI Conference 2026 Conference Paper

Taming the Phantom: Token-Asymmetric Filtering for Hallucination Mitigation in Large Vision-Language Models

  • Shuyi Ouyang
  • Hongyi Wang
  • Gongfan Fang
  • Xinyin Ma
  • Lanfen Lin
  • Xinchao Wang

Hallucination in Large Vision-Language Models (LVLMs) remains a critical challenge, undermining their reliability in real-world applications. Existing studies have investigated the causes of hallucination at the modality level and proposed effective strategies. However, interaction patterns beyond the modality level remain insufficiently explored. In this paper, we conduct a token-level analysis and identify two key phenomena: (1) a small subset of textual tokens in LVLMs exert disproportionate influence in the visual-active layers, surpassing that of the visual modality and potentially misleading visual understanding; (2) while LVLMs can correctly identify key visual information, insufficient focus on these cues can sometimes lead to hallucinations. Based on such observation, we attribute hallucinations in LVLMs to two token-level causes: the disproportionate influence of certain textual tokens (phantom tokens) and the underutilization of critical visual cues (anchor tokens). To mitigate these issues, we introduce Token-Asymmetric Filtering (TAF)—a training-free, plug-and-play method that modulates intermediate attention maps in LVLMs. TAF isolates the influence of phantom tokens and emphasizes the influence of anchor tokens in the visual-active layers. Experimental results across multiple benchmarks demonstrate that TAF significantly mitigates hallucinations across a range of state-of-the-art LVLMs.

AAAI Conference 2025 Conference Paper

M2OST: Many-to-one Regression for Predicting Spatial Transcriptomics from Digital Pathology Images

  • Hongyi Wang
  • Xiuju Du
  • Jing Liu
  • Shuyi Ouyang
  • Yen-Wei Chen
  • Lanfen Lin

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its acquisition cost remains expensive. Therefore, directly predicting the ST expressions from digital pathology images is desired. Current methods usually adopt existing regression backbones along with patch-sampling for this task, which ignores the inherent multi-scale information embedded in the pyramidal data structure of digital pathology images, and wastes the inter-spot visual information crucial for accurate gene expression prediction. To address these limitations, we propose M2OST, a many-to-one regression Transformer that can accommodate the hierarchical structure of the pathology images via a decoupled multi-scale feature extractor. Unlike traditional models that are trained with one-to-one image-label pairs, M2OST uses multiple images from different levels of the digital pathology image to jointly predict the gene expressions in their common corresponding spot. Built upon our many-to-one scheme, M2OST can be easily scaled to fit different numbers of inputs, and its network structure inherently incorporates nearby inter-spot features, enhancing regression performance. We have tested M2OST on three public ST datasets and the experimental results show that M2OST can achieve state-of-the-art performance with fewer parameters and floating-point operations (FLOPs).

JBHI Journal 2025 Journal Article

S 2 Match: Revisiting Weak-to-Strong Consistency from a Semantic Similarity Perspective for Semi-supervised Medical Image Segmentation

  • Shiao Xie
  • Hongyi Wang
  • Ziwei Niu
  • Hao Sun
  • Shuyi Ouyang
  • Yen-Wei Chen
  • Lanfen Lin

Semi-supervised learning (SSL) for medical image segmentation is a challenging yet highly practical task, which reduces reliance on large-scale labeled datasets by leveraging unlabeled samples. Among SSL techniques, the weak-to-strong consistency framework, popularized by FixMatch, has emerged as a state-of-the-art method in classification tasks. Notably, such a simple pipeline has also shown competitive performance in medical image segmentation. However, two key limitations still persist, impeding its efficient adaptation: (1) the neglect of contextual dependencies results in inconsistent predictions for similar semantic features, leading to incomplete object segmentation; (2) the lack of exploitation on semantic similarity between labeled and unlabeled data induces considerable class-distribution discrepancy. To address these limitations, we propose a novel SSL framework for medical image segmentation, named S 2 Match, powered by two appealing designs from a semantic similarity perspective: (1) rectifying pixel-wise prediction by reasoning about the intra-image pair-wise affinity map, thus integrating contextual dependencies explicitly into the final prediction; (2) bridging labeled and unlabeled data via a feature querying mechanism for compact class representation learning, which fully considers cross-image anatomical similarities. As the reliable semantic similarity extraction depends on robust features, we further introduce an effective Spatial-aware Fusion Module (SFM) to explore distinctive information from multiple scales. Experiments show that S 2 Match yields consistent improvements over the state-of-the-art methods across five public medical image segmentation benchmarks, exhibiting competitive performance on both 2D and 3D tasks.

ICML Conference 2025 Conference Paper

Understanding the Forgetting of (Replay-based) Continual Learning via Feature Learning: Angle Matters

  • Hongyi Wang
  • Shiyuan Ren
  • Wei Huang 0034
  • Miao Zhang 0001
  • Xiang Deng 0002
  • Yixin Bao
  • Liqiang Nie

Continual learning (CL) is crucial for advancing human-level intelligence, but its theoretical understanding, especially regarding factors influencing forgetting, is still relatively limited. This work aims to build a unified theoretical framework for understanding CL using feature learning theory. Different from most existing studies that analyze forgetting under linear regression model or lazy training, we focus on a more practical two-layer convolutional neural network (CNN) with polynomial ReLU activation for sequential tasks within a signal-noise data model. Specifically, we theoretically reveal how the angle between task signal vectors influences forgetting that: acute or small obtuse angles lead to benign forgetting, whereas larger obtuse angles result in harmful forgetting. Furthermore, we demonstrate that the replay method alleviates forgetting by expanding the range of angles corresponding to benign forgetting. Our theoretical results suggest that mid-angle sampling, which selects examples with moderate angles to the prototype, can enhance the replay method’s ability to mitigate forgetting. Experiments on synthetic and real-world datasets confirm our theoretical results and highlight the effectiveness of our mid-angle sampling strategy.

NeurIPS Conference 2024 Conference Paper

$\texttt{Model-GLUE}$: Democratized LLM Scaling for A Large Model Zoo in the Wild

  • Xinyu Zhao
  • Guoheng Sun
  • Ruisi Cai
  • Yukun Zhou
  • Pingzhi Li
  • Peihao Wang
  • Bowen Tan
  • Yexiao He

As Large Language Models (LLMs) excel across tasks and specialized domains, scaling LLMs based on existing models has gained significant attention, which is challenged by potential performance drop when combining disparate models. Various techniques have been proposed to aggregate pre-trained LLMs, including model merging, Mixture-of-Experts, and stacking. Despite their merits, a comprehensive comparison and synergistic application of them to a diverse model zoo is yet to be adequately addressed. In light of this research gap, this paper introduces $\texttt{Model-GLUE}$, a holistic LLM scaling guideline. First, our work starts with a benchmarking of existing LLM scaling techniques, especially selective merging, and variants of mixture. Utilizing the insights from the benchmark results, we formulate a strategy for the selection and aggregation of a heterogeneous model zoo characterizing different architectures and initialization. Our methodology involves clustering mergeable models, selecting a merging strategy, and integrating model clusters through model-level mixture. Finally, evidenced by our experiments on a diverse Llama-2-based model zoo, $\texttt{Model-GLUE}$ shows an average performance enhancement of 5. 61\%, achieved without additional training. Codes are available at https: //github. com/Model-GLUE/Model-GLUE.

NeurIPS Conference 2024 Conference Paper

FLoRA: Federated Fine-Tuning Large Language Models with Heterogeneous Low-Rank Adaptations

  • Ziyao Wang
  • Zheyu Shen
  • Yexiao He
  • Guoheng Sun
  • Hongyi Wang
  • Lingjuan Lyu
  • Ang Li

The rapid development of Large Language Models (LLMs) has been pivotal in advancing AI, with pre-trained LLMs being adaptable to diverse downstream tasks through fine-tuning. Federated learning (FL) further enhances fine-tuning in a privacy-aware manner by utilizing clients' local data through in-situ computation, eliminating the need for data movement. However, fine-tuning LLMs, given their massive scale of parameters, poses challenges for clients with constrained and heterogeneous resources in FL. Previous methods employed low-rank adaptation (LoRA) for efficient federated fine-tuning but utilized traditional FL aggregation strategies on LoRA adapters. This approach led to mathematically inaccurate aggregation noise, reducing fine-tuning effectiveness and failing to address heterogeneous LoRAs. In this work, we first highlight the mathematical incorrectness of LoRA aggregation in existing federated fine-tuning methods. We introduce a new approach called FLoRA that enables federated fine-tuning on heterogeneous LoRA adapters across clients through a novel stacking-based aggregation method. Our approach is noise-free and seamlessly supports heterogeneous LoRAs. Extensive experiments demonstrate FLoRA's superior performance in both homogeneous and heterogeneous settings, surpassing state-of-the-art methods. We envision this work as a milestone for efficient, privacy-preserving, and accurate federated fine-tuning of LLMs.

NeurIPS Conference 2024 Conference Paper

SHED: Shapley-Based Automated Dataset Refinement for Instruction Fine-Tuning

  • Yexiao He
  • Ziyao Wang
  • Zheyu Shen
  • Guoheng Sun
  • Yucong Dai
  • Yongkai Wu
  • Hongyi Wang
  • Ang Li

The pre-trained Large Language Models (LLMs) can be adapted for many downstream tasks and tailored to align with human preferences through fine-tuning. Recent studies have discovered that LLMs can achieve desirable performance with only a small amount of high-quality data, suggesting that a large portion of the data in these extensive datasets is redundant or even harmful. Identifying high-quality data from vast datasets to curate small yet effective datasets has emerged as a critical challenge. In this paper, we introduce SHED, an automated dataset refinement framework based on Shapley value for instruction fine-tuning. SHED eliminates the need for human intervention or the use of commercial LLMs. Moreover, the datasets curated through SHED exhibit transferability, indicating they can be reused across different LLMs with consistently high performance. We conduct extensive experiments to evaluate the datasets curated by SHED. The results demonstrate SHED's superiority over state-of-the-art methods across various tasks and LLMs; notably, datasets comprising only 10% of the original data selected by SHED achieve performance comparable to or surpassing that of the full datasets.

JBHI Journal 2023 Journal Article

Adaptive Decomposition and Shared Weight Volumetric Transformer Blocks for Efficient Patch-Free 3D Medical Image Segmentation

  • Hongyi Wang
  • Yingying Xu
  • Qingqing Chen
  • Ruofeng Tong
  • Yen-Wei Chen
  • Hongjie Hu
  • Lanfen Lin

High resolution (HR) 3D medical image segmentation is vital for an accurate diagnosis. However, in the field of medical imaging, it is still a challenging task to achieve a high segmentation performance with cost-effective and feasible computation resources. Previous methods commonly use patch-sampling to reduce the input size, but this inevitably harms the global context and decreases the model's performance. In recent years, a few patch-free strategies have been presented to deal with this issue, but either they have limited performance due to their over-simplified model structures or they follow a complicated training process. In this study, to effectively address these issues, we present Adaptive Decomposition (A-Decomp) and Shared Weight Volumetric Transformer Blocks (SW-VTB). A-Decomp can adaptively decompose features and reduce their spatial size, which greatly lowers GPU memory consumption. SW-VTB is able to capture long-range dependencies at a low cost with its lightweight design and cross-scale weight-sharing mechanism. Our proposed cross-scale weight-sharing approach enhances the network's ability to capture scale-invariant core semantic information in addition to reducing parameter numbers. By combining these two designs together, we present a novel patch-free segmentation framework named VolumeFormer. Experimental results on two datasets show that VolumeFormer outperforms existing patch-based and patch-free methods with a comparatively fast inference speed and relatively compact design.

NeurIPS Conference 2023 Conference Paper

FedNAR: Federated Optimization with Normalized Annealing Regularization

  • Junbo Li
  • Ang Li
  • Chong Tian
  • Qirong Ho
  • Eric Xing
  • Hongyi Wang

Weight decay is a standard technique to improve generalization performance in modern deep neural network optimization, and is also widely adopted in federated learning (FL) to prevent overfitting in local clients. In this paper, we first explore the choices of weight decay and identify that weight decay value appreciably influences the convergence of existing FL algorithms. While preventing overfitting is crucial, weight decay can introduce a different optimization goal towards the global objective, which is further amplified in FL due to multiple local updates and heterogeneous data distribution. To address this challenge, we develop {\it Federated optimization with Normalized Annealing Regularization} (FedNAR), a simple yet effective and versatile algorithmic plug-in that can be seamlessly integrated into any existing FL algorithms. Essentially, we regulate the magnitude of each update by performing co-clipping of the gradient and weight decay. We provide a comprehensive theoretical analysis of FedNAR's convergence rate and conduct extensive experiments on both vision and language datasets with different backbone federated optimization algorithms. Our experimental results consistently demonstrate that incorporating FedNAR into existing FL algorithms leads to accelerated convergence and heightened model accuracy. Moreover, FedNAR exhibits resilience in the face of various hyperparameter configurations. Specifically, FedNAR has the ability to self-adjust the weight decay when the initial specification is not optimal, while the accuracy of traditional FL algorithms would markedly decline. Our codes are released at \href{https: //anonymous. 4open. science/r/fednar-BE8F}{https: //anonymous. 4open. science/r/fednar-BE8F}.

IJCAI Conference 2023 Conference Paper

SLViT: Scale-Wise Language-Guided Vision Transformer for Referring Image Segmentation

  • Shuyi Ouyang
  • Hongyi Wang
  • Shiao Xie
  • Ziwei Niu
  • Ruofeng Tong
  • Yen-Wei Chen
  • Lanfen Lin

Referring image segmentation aims to segment an object out of an image via a specific language expression. The main concept is establishing global visual-linguistic relationships to locate the object and identify boundaries using details of the image. Recently, various Transformer-based techniques have been proposed to efficiently leverage long-range cross-modal dependencies, enhancing performance for referring segmentation. However, existing methods consider visual feature extraction and cross-modal fusion separately, resulting in insufficient visual-linguistic alignment in semantic space. In addition, they employ sequential structures and hence lack multi-scale information interaction. To address these limitations, we propose a Scale-Wise Language-Guided Vision Transformer (SLViT) with two appealing designs: (1) Language-Guided Multi-Scale Fusion Attention, a novel attention mechanism module for extracting rich local visual information and modeling global visual-linguistic relationships in an integrated manner. (2) An Uncertain Region Cross-Scale Enhancement module that can identify regions of high uncertainty using linguistic features and refine them via aggregated multi-scale features. We have evaluated our method on three benchmark datasets. The experimental results demonstrate that SLViT surpasses state-of-the-art methods with lower computational cost. The code is publicly available at: https: //github. com/NaturalKnight/SLViT.

NeurIPS Conference 2022 Conference Paper

AMP: Automatically Finding Model Parallel Strategies with Heterogeneity Awareness

  • Dacheng Li
  • Hongyi Wang
  • Eric Xing
  • Hao Zhang

Scaling up model sizes can lead to fundamentally new capabilities in many machine learning (ML) tasks. However, training big models requires strong distributed system expertise to carefully design model-parallel execution strategies that suit the model architectures and cluster setups. In this paper, we develop AMP, a framework that automatically derives such strategies. AMP identifies a valid space of model parallelism strategies and efficiently searches the space for high-performed strategies, by leveraging a cost model designed to capture the heterogeneity of the model and cluster specifications. Unlike existing methods, AMP is specifically tailored to support complex models composed of uneven layers and cluster setups with more heterogeneous accelerators and bandwidth. We evaluate AMP on popular modelsand cluster setups from public clouds and show that AMP returns parallel strategies that match the expert-tuned strategies on typical cluster setups. On heterogeneous clusters or models with heterogeneous architectures, AMP finds strategies with 1. 54$\times$ and 1. 77$\times$ higher throughput than state-of-the-art model-parallel systems, respectively.

NeurIPS Conference 2022 Conference Paper

Rare Gems: Finding Lottery Tickets at Initialization

  • Kartik Sreenivasan
  • Jy-yong Sohn
  • Liu Yang
  • Matthew Grinde
  • Alliot Nagle
  • Hongyi Wang
  • Eric Xing
  • Kangwook Lee

Large neural networks can be pruned to a small fraction of their original size, with little loss in accuracy, by following a time-consuming "train, prune, re-train" approach. Frankle & Carbin conjecture that we can avoid this by training lottery tickets, i. e. , special sparse subnetworks found at initialization, that can be trained to high accuracy. However, a subsequent line of work presents concrete evidence that current algorithms for finding trainable networks at initialization, fail simple baseline comparisons, e. g. , against training random sparse subnetworks. Finding lottery tickets that train to better accuracy compared to simple baselines remains an open problem. In this work, we resolve this open problem by proposing Gem-Miner which finds lottery tickets at initialization that beat current baselines. Gem-Miner finds lottery tickets trainable to accuracy competitive or better than Iterative Magnitude Pruning (IMP), and does so up to $19\times$ faster.

NeurIPS Conference 2020 Conference Paper

Attack of the Tails: Yes, You Really Can Backdoor Federated Learning

  • Hongyi Wang
  • Kartik Sreenivasan
  • Shashank Rajput
  • Harit Vishwakarma
  • Saurabh Agarwal
  • Jy-yong Sohn
  • Kangwook Lee
  • Dimitris Papailiopoulos

Due to its decentralized nature, Federated Learning (FL) lends itself to adversarial attacks in the form of backdoors during training. The goal of a backdoor is to corrupt the performance of the trained model on specific sub-tasks (e. g. , by classifying green cars as frogs). A range of FL backdoor attacks have been introduced in the literature, but also methods to defend against them, and it is currently an open question whether FL systems can be tailored to be robust against backdoors. In this work, we provide evidence to the contrary. We first establish that, in the general case, robustness to backdoors implies model robustness to adversarial examples, a major open problem in itself. Furthermore, detecting the presence of a backdoor in a FL model is unlikely assuming first-order oracles or polynomial time. We couple our theoretical results with a new family of backdoor attacks, which we refer to as edge-case backdoors. An edge-case backdoor forces a model to misclassify on seemingly easy inputs that are however unlikely to be part of the training, or test data, i. e. , they live on the tail of the input distribution. We explain how these edge-case backdoors can lead to unsavory failures and may have serious repercussions on fairness. We further exhibit that, with careful tuning at the side of the adversary, one can insert them across a range of machine learning tasks (e. g. , image classification, OCR, text prediction, sentiment analysis), and bypass state-of-the-art defense mechanisms.

NeurIPS Conference 2019 Conference Paper

DETOX: A Redundancy-based Framework for Faster and More Robust Gradient Aggregation

  • Shashank Rajput
  • Hongyi Wang
  • Zachary Charles
  • Dimitris Papailiopoulos

To improve the resilience of distributed training to worst-case, or Byzantine node failures, several recent methods have replaced gradient averaging with robust aggregation methods. Such techniques can have high computational costs, often quadratic in the number of compute nodes, and only have limited robustness guarantees. Other methods have instead used redundancy to guarantee robustness, but can only tolerate limited numbers of Byzantine failures. In this work, we present DETOX, a Byzantine-resilient distributed training framework that combines algorithmic redundancy with robust aggregation. DETOX operates in two steps, a filtering step that uses limited redundancy to significantly reduce the effect of Byzantine nodes, and a hierarchical aggregation step that can be used in tandem with any state-of-the-art robust aggregation method. We show theoretically that this leads to a substantial increase in robustness, and has a per iteration runtime that can be nearly linear in the number of compute nodes. We provide extensive experiments over real distributed setups across a variety of large-scale machine learning tasks, showing that DETOX leads to orders of magnitude accuracy and speedup improvements over many state-of-the-art Byzantine-resilient approaches.

NeurIPS Conference 2018 Conference Paper

ATOMO: Communication-efficient Learning via Atomic Sparsification

  • Hongyi Wang
  • Scott Sievert
  • Shengchao Liu
  • Zachary Charles
  • Dimitris Papailiopoulos
  • Stephen Wright

Distributed model training suffers from communication overheads due to frequent gradient updates transmitted between compute nodes. To mitigate these overheads, several studies propose the use of sparsified stochastic gradients. We argue that these are facets of a general sparsification method that can operate on any possible atomic decomposition. Notable examples include element-wise, singular value, and Fourier decompositions. We present ATOMO, a general framework for atomic sparsification of stochastic gradients. Given a gradient, an atomic decomposition, and a sparsity budget, ATOMO gives a random unbiased sparsification of the atoms minimizing variance. We show that recent methods such as QSGD and TernGrad are special cases of ATOMO, and that sparsifiying the singular value decomposition of neural networks gradients, rather than their coordinates, can lead to significantly faster distributed training.

NeurIPS Conference 2018 Conference Paper

The Effect of Network Width on the Performance of Large-batch Training

  • Lingjiao Chen
  • Hongyi Wang
  • Jinman Zhao
  • Dimitris Papailiopoulos
  • Paraschos Koutris

Distributed implementations of mini-batch stochastic gradient descent (SGD) suffer from communication overheads, attributed to the high frequency of gradient updates inherent in small-batch training. Training with large batches can reduce these overheads; however it besets the convergence of the algorithm and the generalization performance. In this work, we take a first step towards analyzing how the structure (width and depth) of a neural network affects the performance of large-batch training. We present new theoretical results which suggest that--for a fixed number of parameters--wider networks are more amenable to fast large-batch training compared to deeper ones. We provide extensive experiments on residual and fully-connected neural networks which suggest that wider networks can be trained using larger batches without incurring a convergence slow-down, unlike their deeper variants.

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