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Haolin Li

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NeurIPS Conference 2025 Conference Paper

Exploring Semantic-constrained Adversarial Example with Instruction Uncertainty Reduction

  • Jin Hu
  • Jiakai Wang
  • linna Jing
  • Haolin Li
  • Liu haodong
  • Haotong Qin
  • Aishan Liu
  • Ke Xu

Recently, semantically constrained adversarial examples (SemanticAE), which are directly generated from natural language instructions, have become a promising avenue for future research due to their flexible attacking forms, but have not been thoroughly explored yet. To generate SemanticAEs, current methods fall short of satisfactory attacking ability as the key underlying factors of semantic uncertainty in human instructions, such as $\textit{referring diversity}$, $\textit{descriptive incompleteness}$, and $\textit{boundary ambiguity}$, have not been fully investigated. To tackle the issues, this paper develops a multi-dimensional $\textbf{ins}$truction $\textbf{u}$ncertainty $\textbf{r}$eduction ($\textbf{InSUR}$) framework to generate more satisfactory SemanticAE, $\textit{i. e. }$, transferable, adaptive, and effective. Specifically, in the dimension of the sampling method, we propose the residual-driven attacking direction stabilization to alleviate the unstable adversarial optimization caused by the diversity of language references. By coarsely predicting the language-guided sampling process, the optimization process will be stabilized by the designed ResAdv-DDIM sampler, therefore releasing the transferable and robust adversarial capability of multi-step diffusion models. In task modeling, we propose the context-encoded attacking scenario constraint to supplement the missing knowledge from incomplete human instructions. Guidance masking and renderer integration are proposed to regulate the constraints of 2D/3D SemanticAE, activating stronger scenario-adapted attacks. Moreover, in the dimension of generator evaluation, we propose the semantic-abstracted attacking evaluation enhancement by clarifying the evaluation boundary based on the label taxonomy, facilitating the development of more effective SemanticAE generators. Extensive experiments demonstrate the superiority of the transfer attack performance of InSUR. Besides, it is worth highlighting that we realize the reference-free generation of semantically constrained 3D adversarial examples by utilizing language-guided 3D generation models for the first time.

NeurIPS Conference 2025 Conference Paper

RAD: Towards Trustworthy Retrieval-Augmented Multi-modal Clinical Diagnosis

  • Haolin Li
  • Tianjie Dai
  • Zhe Chen
  • Siyuan Du
  • Jiangchao Yao
  • Ya Zhang
  • Yanfeng Wang

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text pretraining paradigms to incorporate medical knowledge, these approaches primarily rely on implicitly encoded knowledge within model parameters, neglecting task-specific knowledge required by diverse downstream tasks. To address this limitation, we propose R etrieval- A ugmented D iagnosis (RAD), a novel framework that explicitly injects external knowledge into multimodal models directly on downstream tasks. Specifically, RAD operates through three key mechanisms: retrieval and refinement of disease-centered knowledge from multiple medical sources, a guideline-enhanced contrastive loss that constrains the latent distance between multi-modal features and guideline knowledge, and the dual transformer decoder that employs guidelines as queries to steer cross-modal fusion, aligning the models with clinical diagnostic workflows from guideline acquisition to feature extraction and decision-making. Moreover, recognizing the lack of quantitative evaluation of interpretability for multimodal diagnostic models, we introduce a set of criteria to assess the interpretability from both image and text perspectives. Extensive evaluations across four datasets with different anatomies demonstrate RAD's generalizability, achieving state-of-the-art performance. Furthermore, RAD enables the model to concentrate more precisely on abnormal regions and critical indicators, ensuring evidence-based, trustworthy diagnosis. Our code is available at https: //github. com/tdlhl/RAD.

v2026.09.13