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Guoxin Chen

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4 papers

2 author rows

ICML Conference 2025 Conference Paper

C-3PO: Compact Plug-and-Play Proxy Optimization to Achieve Human-like Retrieval-Augmented Generation

Guoxin Chen
Minpeng Liao
Peiying Yu
Dingmin Wang
Zile Qiao
Chao Yang
Xin Zhao 0018
Kai Fan 0002

Retrieval-augmented generation (RAG) systems face a fundamental challenge in aligning independently developed retrievers and large language models (LLMs). Existing approaches typically involve modifying either component or introducing simple intermediate modules, resulting in practical limitations and sub-optimal performance. Inspired by human search behavior—typically involving a back-and-forth process of proposing search queries and reviewing documents, we propose C-3PO, a proxy-centric framework that facilitates communication between retrievers and LLMs through a lightweight multi-agent system. Our framework implements three specialized agents that collaboratively optimize the entire RAG pipeline without altering the retriever and LLMs. These agents work together to assess the need for retrieval, generate effective queries, and select information suitable for the LLMs. To enable effective multi-agent coordination, we develop a tree-structured rollout approach for reward credit assignment in reinforcement learning. Extensive experiments in both in-domain and out-of-distribution scenarios demonstrate that C-3PO significantly enhances RAG performance while maintaining plug-and-play flexibility and superior generalization capabilities.

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ICLR Conference 2025 Conference Paper

Learning Evolving Tools for Large Language Models

Guoxin Chen
Zhong Zhang 0004
Xin Cong
Fangda Guo
Yesai Wu
Yankai Lin 0001
Wenzheng Feng
Yasheng Wang

Tool learning enables large language models (LLMs) to interact with external tools and APIs, greatly expanding the application scope of LLMs. However, due to the dynamic nature of external environments, these tools and APIs may become outdated over time, preventing LLMs from correctly invoking tools. Existing research primarily focuses on static environments and overlooks this issue, limiting the adaptability of LLMs in real-world applications. In this paper, we propose ToolEVO, a novel framework designed to enhance the adaptive and reflective capabilities of LLMs against tool variability. By leveraging Monte Carlo Tree Search, ToolEVO facilitates active exploration and interaction of LLMs within dynamic environments, allowing for autonomous self-reflection and self-updating of tool usage based on environmental feedback. Additionally, we introduce ToolQA-D, a benchmark specifically designed to evaluate the impact of tool variability. Extensive experiments demonstrate the effectiveness and stability of our approach, highlighting the importance of adaptability to tool variability for effective tool learning.

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NeurIPS Conference 2024 Conference Paper

AlphaMath Almost Zero: Process Supervision without Process

Guoxin Chen
Minpeng Liao
Chengxi Li
Kai Fan

Although recent advancements in large language models (LLMs) have significantly improved their performance on various tasks, they still face challenges with complex and symbolic multi-step reasoning, particularly in mathematical reasoning. To bolster the mathematical reasoning capabilities of LLMs, most existing efforts concentrate on seeking assistance from either domain experts or GPT-4 for high-quality process-supervised data, which is not only expensive but also labor-intensive. In our study, we propose an innovative framework, AlphaMath, that bypasses the need for process annotations (from humans or GPTs) by leveraging Monte Carlo Tree Search (MCTS). This framework focuses on unleashing the potential of a well-pretrained LLM to autonomously enhance its mathematical reasoning. Specifically, we integrate a value model with the LLM, automatically generating both process supervision and step-level evaluation signals in MCTS. Furthermore, we propose an efficient inference strategy—step-level beam search, where the value model is crafted to assist the policy model (i. e. , LLM) in navigating more effective reasoning paths, rather than solely relying on prior probabilities. The experimental results on both in-domain and out-of-domain datasets demonstrate that even without GPT-4 or human-annotated process supervision, our AlphaMath framework achieves comparable or superior results to previous state-of-the-art methods.

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NeurIPS Conference 2024 Conference Paper

DiReCT: Diagnostic Reasoning for Clinical Notes via Large Language Models

Bowen Wang
Jiuyang Chang
Yiming Qian
Guoxin Chen
Junhao Chen
Zhouqiang Jiang
Jiahao Zhang
Yuta Nakashima

Large language models (LLMs) have recently showcased remarkable capabilities, spanning a wide range of tasks and applications, including those in the medical domain. Models like GPT-4 excel in medical question answering but may face challenges in the lack of interpretability when handling complex tasks in real clinical settings. We thus introduce the diagnostic reasoning dataset for clinical notes (DiReCT), aiming at evaluating the reasoning ability and interpretability of LLMs compared to human doctors. It contains 511 clinical notes, each meticulously annotated by physicians, detailing the diagnostic reasoning process from observations in a clinical note to the final diagnosis. Additionally, a diagnostic knowledge graph is provided to offer essential knowledge for reasoning, which may not be covered in the training data of existing LLMs. Evaluations of leading LLMs on DiReCT bring out a significant gap between their reasoning ability and that of human doctors, highlighting the critical need for models that can reason effectively in real-world clinical scenarios.

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