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Dongang Wang

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AAAI Conference 2025 Conference Paper

Overcoming Heterogeneous Data in Federated Medical Vision-Language Pre-training: A Triple-Embedding Model Selector Approach

  • Aowen Wang
  • Zhiwang Zhang
  • Dongang Wang
  • Fanyi Wang
  • Haotian Hu
  • Jinyang Guo
  • Yipeng Zhou
  • Chaoyi Pang

The scarcity data of medical field brings the collaborative training in medical vision-language pre-training (VLP) cross different clients. Therefore, the collaborative training in medical VLP faces two challenges: First, the medical data requires privacy, thus can not directly shared across different clients. Second, medical data distribution across institutes is typically heterogeneous, hindering local model alignment and representation capabilities. To simultaneously overcome these two challenges, we propose the framework called personalized model selector with fused multimodal information (PMS-FM). The contribution of PMS-FM is two-fold: 1) PMS-FM uses embeddings to represent information in different formats, allowing for the fusion of multimodal data. 2) PMS-FM adapts to personalized data distributions by training multiple models. A model selector then identifies and selects the best-performing model for each individual client. Extensive experiments with multiple real-world medical datasets demonstrate the superb performance of PMS-FM over existing federated learning methods on different zero-shot classification tasks.

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AIIM Journal 2024 Journal Article

Improving multiple sclerosis lesion segmentation across clinical sites: A federated learning approach with noise-resilient training

  • Lei Bai
  • Dongang Wang
  • Hengrui Wang
  • Michael Barnett
  • Mariano Cabezas
  • Weidong Cai
  • Fernando Calamante
  • Kain Kyle

Accurately measuring the evolution of Multiple Sclerosis (MS) with magnetic resonance imaging (MRI) critically informs understanding of disease progression and helps to direct therapeutic strategy. Deep learning models have shown promise for automatically segmenting MS lesions, but the scarcity of accurately annotated data hinders progress in this area. Obtaining sufficient data from a single clinical site is challenging and does not address the heterogeneous need for model robustness. Conversely, the collection of data from multiple sites introduces data privacy concerns and potential label noise due to varying annotation standards. To address this dilemma, we explore the use of the federated learning framework while considering label noise. Our approach enables collaboration among multiple clinical sites without compromising data privacy under a federated learning paradigm that incorporates a noise-robust training strategy based on label correction. Specifically, we introduce a Decoupled Hard Label Correction (DHLC) strategy that considers the imbalanced distribution and fuzzy boundaries of MS lesions, enabling the correction of false annotations based on prediction confidence. We also introduce a Centrally Enhanced Label Correction (CELC) strategy, which leverages the aggregated central model as a correction teacher for all sites, enhancing the reliability of the correction process. Extensive experiments conducted on two multi-site datasets demonstrate the effectiveness and robustness of our proposed methods, indicating their potential for clinical applications in multi-site collaborations to train better deep learning models with lower cost in data collection and annotation.

Details DOI
v2026.09.13