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Chengwei Pan

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5 papers
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5

AAAI Conference 2025 Conference Paper

AGFSync: Leveraging AI-Generated Feedback for Preference Optimization in Text-to-Image Generation

  • Jingkun An
  • Yinghao Zhu
  • Zongjian Li
  • Enshen Zhou
  • Haoran Feng
  • Xijie Huang
  • Bohua Chen
  • Yemin Shi

Text-to-Image (T2I) diffusion models have achieved remarkable success in image generation. Despite their progress, challenges remain in both prompt-following ability, image quality and lack of high-quality datasets, which are essential for refining these models. As acquiring labeled data is costly, we introduce AGFSync, a framework that enhances T2I diffusion models through Direct Preference Optimization (DPO) in a fully AI-driven approach. AGFSync utilizes Vision-Language Models (VLM) to assess image quality across style, coherence, and aesthetics, generating feedback data within an AI-driven loop. By applying AGFSync to leading T2I models such as SD v1.4, v1.5, and SDXL-base, our extensive experiments on the TIFA dataset demonstrate notable improvements in VQA scores, aesthetic evaluations, and performance on the HPS v2 benchmark, consistently outperforming the base models. AGFSync's method of refining T2I diffusion models paves the way for scalable alignment techniques.

AAAI Conference 2025 Conference Paper

Medical MLLM Is Vulnerable: Cross-Modality Jailbreak and Mismatched Attacks on Medical Multimodal Large Language Models

  • Xijie Huang
  • Xinyuan Wang
  • Hantao Zhang
  • Yinghao Zhu
  • Jiawen Xi
  • Jingkun An
  • Hao Wang
  • Hao Liang

Security concerns related to Large Language Models (LLMs) have been extensively explored; however, the safety implications for Multimodal Large Language Models (MLLMs), particularly in medical contexts (MedMLLMs), remain inadequately addressed. This paper investigates the security vulnerabilities of MedMLLMs, focusing on their deployment in clinical environments where the accuracy and relevance of question-and-answer interactions are crucial for addressing complex medical challenges. We introduce and redefine two attack types: mismatched malicious attack (2M-attack) and optimized mismatched malicious attack (O2M-attack), by integrating existing clinical data with atypical natural phenomena. Using the comprehensive 3MAD dataset that we developed, which spans a diverse range of medical imaging modalities and adverse medical scenarios, we performed an in-depth analysis and proposed the MCM optimization method. This approach significantly improves the attack success rate against MedMLLMs. Our evaluations, which include white-box attacks on LLaVA-Med and transfer (black-box) attacks on four other SOTA models, reveal that even MedMLLMs designed with advanced security mechanisms remain vulnerable to breaches. This study highlights the critical need for robust security measures to enhance the safety and reliability of open-source MedMLLMs, especially in light of the potential impact of jailbreak attacks and other malicious exploits in clinical applications. Warning: Medical jailbreaking may generate content that includes unverified diagnoses and treatment recommendations. Always consult professional medical advice.

AAAI Conference 2025 Conference Paper

Novel View Synthesis Under Large-Deviation Viewpoint for Autonomous Driving

  • Xin Ma
  • Jiguang Zhang
  • Peng Lu
  • Shibiao Xu
  • Chengwei Pan

Novel view synthesis is a critical task in autonomous driving. Although 3D Gaussian Splatting (3D-GS) has shown success in generating novel views, it faces challenges in maintaining high-quality rendering when viewpoints deviate significantly from the training set. This difficulty primarily stems from complex lighting conditions and geometric inconsistencies in texture-less regions. To address these issues, we propose an attention-based illumination model that leverages light fields from neighboring views, enhancing the realism of synthesized images. Additionally, we propose a geometry optimization method using planar homography to improve geometric consistency in texture-less regions. Our experiments demonstrate substantial improvements in synthesis quality for large-deviation viewpoints, validating the effectiveness of our approach.

JBHI Journal 2022 Journal Article

GREN: Graph-Regularized Embedding Network for Weakly-Supervised Disease Localization in X-Ray Images

  • Baolian Qi
  • Gangming Zhao
  • Xin Wei
  • Changde Du
  • Chengwei Pan
  • Yizhou Yu
  • Jinpeng Li

Locating diseases in chest X-ray images with few careful annotations saves large human effort. Recent works approached this task with innovative weakly-supervised algorithms such as multi-instance learning (MIL) and class activation maps (CAM), however, these methods often yield inaccurate or incomplete regions. One of the reasons is the neglection of the pathological implications hidden in the relationship across anatomical regions within each image and the relationship across images. In this paper, we argue that the cross-region and cross-image relationship, as contextual and compensating information, is vital to obtain more consistent and integral regions. To model the relationship, we propose the Graph Regularized Embedding Network (GREN), which leverages the intra-image and inter-image information to locate diseases on chest X-ray images. GREN uses a pre-trained U-Net to segment the lung lobes, and then models the intra-image relationship between the lung lobes using an intra-image graph to compare different regions. Meanwhile, the relationship between in-batch images is modeled by an inter-image graph to compare multiple images. This process mimics the training and decision-making process of a radiologist: comparing multiple regions and images for diagnosis. In order for the deep embedding layers of the neural network to retain structural information (important in the localization task), we use the Hash coding and Hamming distance to compute the graphs, which are used as regularizers to facilitate training. By means of this, our approach achieves the state-of-the-art result on NIH chest X-ray dataset for weakly-supervised disease localization. Our codes are accessible online.

JBHI Journal 2022 Journal Article

MFI-Net: Multiscale Feature Interaction Network for Retinal Vessel Segmentation

  • Yiwen Ye
  • Chengwei Pan
  • Yicheng Wu
  • Shuqi Wang
  • Yong Xia

Segmentation of retinal vessels on fundus images plays a critical role in the diagnosis of micro-vascular and ophthalmological diseases. Although being extensively studied, this task remains challenging due to many factors including the highly variable vessel width and poor vessel-background contrast. In this paper, we propose a multiscale feature interaction network (MFI-Net) for retinal vessel segmentation, which is a U-shaped convolutional neural network equipped with the pyramid squeeze-and-excitation (PSE) module, coarse-to-fine (C2F) module, deep supervision, and feature fusion. We extend the SE operator to multiscale features, resulting in the PSE module, which uses the channel attention learned at multiple scales to enhance multiscale features and enables the network to handle the vessels with variable width. We further design the C2F module to generate and re-process the residual feature maps, aiming to preserve more vessel details during the decoding process. The proposed MFI-Net has been evaluated against several public models on the DRIVE, STARE, CHASE_DB1, and HRF datasets. Our results suggest that both PSE and C2F modules are effective in improving the accuracy of MFI-Net, and also indicate that our model has superior segmentation performance and generalization ability over existing models on four public datasets.

v2026.09.13