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Chee-Ming Ting

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8 papers
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8

JBHI Journal 2026 Journal Article

A Unified Framework for Sparse Reconstruction via Preconditioning and Nonconvex Regularization

  • Prasad Theeda
  • Fuad Noman
  • Arghya Pal
  • Raphaël C.-W. Phan
  • Hernando Ombao
  • Chee-Ming Ting

Compressed Sensing (CS) is an effective technique to recover sparse signals with fewer samples than what is required by the classical Shannon Nyquist sampling theorem. The sensing matrix, sparsifying transform, and sparse recovery algorithm are three key factors for accurate reconstruction in CS. Traditional CS uses a convex $l_{1}$ -norm sparse regularizer which may lead to biased estimates and is suboptimal in promoting sparsity. Another challenge is the design of incoherent sensing matrices which is crucial for accurate sparse recovery. In this paper, we propose a novel CS framework combining a preconditioned sensing matrix and nonconvex regularization for improved sparse signal recovery. First, we formulate an optimization problem to find an incoherent sensing matrix via a preconditioner. It allows for a direct computation of the optimal preconditioner and preconditioned sensing matrix, simultaneously. Secondly, we consider a generalized CS model for signal recovery based on the incoherent sensing matrix and a nonconvex $\ell _{1/2}$ -norm regularizer. We then derive an Alternating Direction Method of Multipliers (ADMM) algorithm to solve this nonconvex optimization problem. The proposed model is applied to sparse-view Computed Tomography (CT) reconstruction with highly-undersampled and noisy data. Qualitative and quantitative results show significantly better image reconstruction using the preconditioned sensing matrix and $\ell _{1/2}$ regularizer, compared to methods without preconditioning and using the $\ell _{1}$ regularizer.

AAAI Conference 2026 Conference Paper

FLAG-4D: Flow-Guided Local-Global Dual-Deformation Model for 4D Reconstruction

  • Guan Yuan Tan
  • Ngoc Tuan Vu
  • Arghya Pal
  • Sailaja Rajanala
  • Raphael C W Phan
  • Mettu Srinivas
  • Chee-Ming Ting

We introduce FLAG-4D, a novel framework for generating novel views of dynamic scenes by reconstructing how 3D Gaussian primitives evolve through space and time. Existing methods typically rely on a single Multilayer Perceptron(MLP) to model temporal deformations, and they often struggle to capture complex point motions and fine-grained dynamic details consistently over time, especially from sparse input views. Our approach, FLAG-4D overcomes this by employing a dual-deformation network that dynamically warps a canonical set of 3D Gaussians over time into new positions and anisotropic shapes. This dual-deformation network consists of an Instantaneous Deformation Network (IDN) for modeling fine-grained, local deformations, and Global Motion Network (GMN) for capturing long-range dynamics, refined via mutual learning. To ensure these deformations are both accurate and temporally smooth, FLAG-4D incorporates dense motion features from a pretrained optical flow backbone. We fuse these motion cues from adjacent timeframes and use a deformation-guided attention mechanism to align this flow information with the current state of each evolving 3D Gaussian. Extensive experiments demonstrate that FLAG-4D achieves higher-fidelity and more temporally coherent reconstructions with finer detail preservation than state-of-the-art methods.

TMLR Journal 2025 Journal Article

Learning Energy-Based Generative Models via Potential Flow: A Variational Principle Approach to Probability Density Homotopy Matching

  • Junn Yong Loo
  • Leong Fang Yu
  • Michelle Adeline
  • Julia K. Lau
  • Hwa Hui Tew
  • Arghya Pal
  • Vishnu Monn Baskaran
  • Chee-Ming Ting

Energy-based models (EBMs) are a powerful class of probabilistic generative models due to their flexibility and interpretability. However, relationships between potential flows and explicit EBMs remain underexplored, while contrastive divergence training via implicit Markov chain Monte Carlo (MCMC) sampling is often unstable and expensive in high-dimensional settings. In this paper, we propose Variational Potential (VAPO) Flow Bayes, a new energy-based generative framework that eliminates the need for implicit MCMC sampling and does not rely on auxiliary networks or cooperative training. VAPO learns an energy-parameterized potential flow by constructing a flow-driven density homotopy that is matched to the data distribution through a variational loss minimizing the Kullback-Leibler divergence between the flow-driven and marginal homotopies. This principled formulation enables robust and efficient generative modeling while preserving the interpretability of EBMs. Experimental results on image generation, interpolation, out-of-distribution detection, and compositional generation confirm the effectiveness of VAPO, showing that our method performs competitively with existing approaches in terms of sample quality and versatility across diverse generative modeling tasks.

IJCAI Conference 2024 Conference Paper

A Deep Probabilistic Spatiotemporal Framework for Dynamic Graph Representation Learning with Application to Brain Disorder Identification

  • Sin-Yee Yap
  • Junn Yong Loo
  • Chee-Ming Ting
  • Fuad Noman
  • Raphaël C. -W. Phan
  • Adeel Razi
  • David L. Dowe

Recent applications of pattern recognition techniques on brain connectome classification using functional connectivity (FC) are shifting towards acknowledging the non-Euclidean topology and dynamic aspects of brain connectivity across time. In this paper, a deep spatiotemporal variational Bayes (DSVB) framework is proposed to learn time-varying topological structures in dynamic FC networks for identifying autism spectrum disorder (ASD) in human participants. The framework incorporates a spatial-aware recurrent neural network with an attention-based message passing scheme to capture rich spatiotemporal patterns across dynamic FC networks. To overcome model overfitting on limited training datasets, an adversarial training strategy is introduced to learn graph embedding models that generalize well to unseen brain networks. Evaluation on the ABIDE resting-state functional magnetic resonance imaging dataset shows that our proposed framework substantially outperforms state-of-the-art methods in identifying patients with ASD. Dynamic FC analyses with DSVB-learned embeddings reveal apparent group differences between ASD and healthy controls in brain network connectivity patterns and switching dynamics of brain states.

JBHI Journal 2024 Journal Article

Graph Autoencoders for Embedding Learning in Brain Networks and Major Depressive Disorder Identification

  • Fuad Noman
  • Chee-Ming Ting
  • Hakmook Kang
  • Raphaël C.-W. Phan
  • Hernando Ombao

Brain functional connectivity (FC) networks inferred from functional magnetic resonance imaging (fMRI) have shown altered or aberrant brain functional connectome in various neuropsychiatric disorders. Recent application of deep neural networks to connectome-based classification mostly relies on traditional convolutional neural networks (CNNs) using input FCs on a regular Euclidean grid to learn spatial maps of brain networks neglecting the topological information of the brain networks, leading to potentially sub-optimal performance in brain disorder identification. We propose a novel graph deep learning framework that leverages non-Euclidean information inherent in the graph structure for classifying brain networks in major depressive disorder (MDD). We introduce a novel graph autoencoder (GAE) architecture, built upon graph convolutional networks (GCNs), to embed the topological structure and node content of large fMRI networks into low-dimensional representations. For constructing the brain networks, we employ the Ledoit-Wolf (LDW) shrinkage method to efficiently estimate high-dimensional FC metrics from fMRI data. We explore both supervised and unsupervised techniques for graph embedding learning. The resulting embeddings serve as feature inputs for a deep fully-connected neural network (FCNN) to distinguish MDD from healthy controls (HCs). Evaluating our model on resting-state fMRI MDD dataset, we observe that the GAE-FCNN outperforms several state-of-the-art methods for brain connectome classification, achieving the highest accuracy when using LDW-FC edges as node features. The graph embeddings of fMRI FC networks also reveal significant group differences between MDD and HCs. Our framework demonstrates the feasibility of learning graph embeddings from brain networks, providing valuable discriminative information for diagnosing brain disorders.

JBHI Journal 2020 Journal Article

A Markov-Switching Model Approach to Heart Sound Segmentation and Classification

  • Fuad Noman
  • Sh-Hussain Salleh
  • Chee-Ming Ting
  • S. Balqis Samdin
  • Hernando Ombao
  • Hadri Hussain

Objective: We consider challenges in accurate segmentation of heart sound signals recorded under noisy clinical environments for subsequent classification of pathological events. Existing state-of-the-art solutions to heart sound segmentation use probabilistic models such as hidden Markov models (HMMs), which, however, are limited by its observation independence assumption and rely on pre-extraction of noise-robust features. Methods: We propose a Markov-switching autoregressive (MSAR) process to model the raw heart sound signals directly, which allows efficient segmentation of the cyclical heart sound states according to the distinct dependence structure in each state. To enhance robustness, we extend the MSAR model to a switching linear dynamic system (SLDS) that jointly model both the switching AR dynamics of underlying heart sound signals and the noise effects. We introduce a novel algorithm via fusion of switching Kalman filter and the duration-dependent Viterbi algorithm, which incorporates the duration of heart sound states to improve state decoding. Results: Evaluated on Physionet/CinC Challenge 2016 dataset, the proposed MSAR-SLDS approach significantly outperforms the hidden semi-Markov model (HSMM) in heart sound segmentation based on raw signals and comparable to a feature-based HSMM. The segmented labels were then used to train Gaussian-mixture HMM classifier for identification of abnormal beats, achieving high average precision of 86. 1% on the same dataset including very noisy recordings. Conclusion: The proposed approach shows noticeable performance in heart sound segmentation and classification on a large noisy dataset. Significance: It is potentially useful in developing automated heart monitoring systems for pre-screening of heart pathologies.

JBHI Journal 2020 Journal Article

A Multi-Domain Connectome Convolutional Neural Network for Identifying Schizophrenia From EEG Connectivity Patterns

  • Chun-Ren Phang
  • Fuad Noman
  • Hadri Hussain
  • Chee-Ming Ting
  • Hernando Ombao

Objective: We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently for fMRI, and the proposed architectures essentially focused on a single type of connectivity measure. Methods: We propose a deep convolutional neural network (CNN) framework for classification of electroencephalogram (EEG)-derived brain connectome in schizophrenia (SZ). To capture complementary aspects of disrupted connectivity in SZ, we explore combination of various connectivity features consisting of time and frequency-domain metrics of effective connectivity based on vector autoregressive model and partial directed coherence, and complex network measures of network topology. We design a novel multi-domain connectome CNN (MDC-CNN) based on a parallel ensemble of 1D and 2D CNNs to integrate the features from various domains and dimensions using different fusion strategies. We also consider an extension to dynamic brain connectivity using the recurrent neural networks. Results: Hierarchical latent representations learned by the multiple convolutional layers from EEG connectivity reveals apparent group differences between SZ and healthy controls (HC). Results on a large resting-state EEG dataset show that the proposed CNNs significantly outperform traditional support vector machine classifier. The MDC-CNN with combined connectivity features further improves performance over single-domain CNNs using individual features, achieving remarkable accuracy of 91. 69% with a decision-level fusion. Conclusion: The proposed MDC-CNN by integrating information from diverse brain connectivity descriptors is able to accurately discriminate SZ from HC. Significance: The new framework is potentially useful for developing diagnostic tools for SZ and other disorders.

YNIMG Journal 2018 Journal Article

Statistical models for brain signals with properties that evolve across trials

  • Hernando Ombao
  • Mark Fiecas
  • Chee-Ming Ting
  • Yin Fen Low

Most neuroscience cognitive experiments involve repeated presentations of various stimuli across several minutes or a few hours. It has been observed that brain responses, even to the same stimulus, evolve over the course of the experiment. These changes in brain activation and connectivity are believed to be associated with learning and/or habituation. In this paper, we present two general approaches to modeling dynamic brain connectivity using electroencephalograms (EEGs) recorded across replicated trials in an experiment. The first approach is the Markovian regime-switching vector autoregressive model (MS-VAR) which treats EEGs as realizations of an underlying brain process that switches between different states both within a trial and across trials in the entire experiment. The second is the slowly evolutionary locally stationary process (SEv-LSP) which characterizes the observed EEGs as a mixture of oscillatory activities at various frequency bands. The SEv-LSP model captures the dynamic nature of the amplitudes of the band-oscillations and cross-correlations between them. The MS-VAR model is able to capture abrupt changes in the dynamics while the SEv-LSP directly gives interpretable results. Moreover, it is nonparametric and hence does not suffer from model misspecification. For both of these models, time-evolving connectivity metrics in the frequency domain are derived from the model parameters for both functional and effective connectivity. We illustrate these two models for estimating cross-trial connectivity in selective attention using EEG data from an oddball paradigm auditory experiment where the goal is to characterize the evolution of brain responses to target stimuli and to standard tones presented randomly throughout the entire experiment. The results suggest dynamic changes in connectivity patterns over trials with inter-subject variability.