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Canqian Yang

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AAAI Conference 2022 Conference Paper

Interventional Multi-Instance Learning with Deconfounded Instance-Level Prediction

  • Tiancheng Lin
  • Hongteng Xu
  • Canqian Yang
  • Yi Xu

When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of causal inference, such bag contextual prior works as a confounder and may result in model robustness and interpretability issues. Focusing on this problem, we propose a novel interventional multi-instance learning (IMIL) framework to achieve deconfounded instance-level prediction. Unlike traditional likelihood-based strategies, we design an Expectation- Maximization (EM) algorithm based on causal intervention, providing a robust instance selection in the training phase and suppressing the bias caused by the bag contextual prior. Experiments on pathological image analysis demonstrate that our IMIL method substantially reduces false positives and outperforms state-of-the-art MIL methods.

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JBHI Journal 2021 Journal Article

Reinventing 2D Convolutions for 3D Images

  • Jiancheng Yang
  • Xiaoyang Huang
  • Yi He
  • Jingwei Xu
  • Canqian Yang
  • Guozheng Xu
  • Bingbing Ni

There have been considerable debates over 2D and 3D representation learning on 3D medical images. 2D approaches could benefit from large-scale 2D pretraining, whereas they are generally weak in capturing large 3D contexts. 3D approaches are natively strong in 3D contexts, however few publicly available 3D medical dataset is large and diverse enough for universal 3D pretraining. Even for hybrid (2D + 3D) approaches, the intrinsic disadvantages within the 2D/3D parts still exist. In this study, we bridge the gap between 2D and 3D convolutions by reinventing the 2D convolutions. We propose ACS (axial-coronal-sagittal) convolutions to perform natively 3D representation learning, while utilizing the pretrained weights on 2D datasets. In ACS convolutions, 2D convolution kernels are split by channel into three parts, and convoluted separately on the three views (axial, coronal and sagittal) of 3D representations. Theoretically, ANY 2D CNN (ResNet, DenseNet, or DeepLab) is able to be converted into a 3D ACS CNN, with pretrained weight of a same parameter size. Extensive experiments validate the consistent superiority of the pretrained ACS CNNs, over the 2D/3D CNN counterparts with/without pretraining. Even without pretraining, the ACS convolution can be used as a plug-and-play replacement of standard 3D convolution, with smaller model size and less computation.

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v2026.09.13