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Ashwin Nayak

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AAAI Conference 2024 Conference Paper

MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Records

  • Scott L. Fleming
  • Alejandro Lozano
  • William J. Haberkorn
  • Jenelle A. Jindal
  • Eduardo Reis
  • Rahul Thapa
  • Louis Blankemeier
  • Julian Z. Genkins

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on realistic text generation tasks for healthcare remains challenging. Existing question answering datasets for electronic health record (EHR) data fail to capture the complexity of information needs and documentation burdens experienced by clinicians. To address these challenges, we introduce MedAlign, a benchmark dataset of 983 natural language instructions for EHR data. MedAlign is curated by 15 clinicians (7 specialities), includes clinician-written reference responses for 303 instructions, and provides 276 longitudinal EHRs for grounding instruction-response pairs. We used MedAlign to evaluate 6 general domain LLMs, having clinicians rank the accuracy and quality of each LLM response. We found high error rates, ranging from 35% (GPT-4) to 68% (MPT-7B-Instruct), and 8.3% drop in accuracy moving from 32k to 2k context lengths for GPT-4. Finally, we report correlations between clinician rankings and automated natural language generation metrics as a way to rank LLMs without human review. We make MedAlign available under a research data use agreement to enable LLM evaluations on tasks aligned with clinician needs and preferences.

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NeurIPS Conference 2018 Conference Paper

Online Learning of Quantum States

  • Scott Aaronson
  • Xinyi Chen
  • Elad Hazan
  • Satyen Kale
  • Ashwin Nayak

Suppose we have many copies of an unknown n-qubit state $\rho$. We measure some copies of $\rho$ using a known two-outcome measurement E_1, then other copies using a measurement E_2, and so on. At each stage t, we generate a current hypothesis $\omega_t$ about the state $\rho$, using the outcomes of the previous measurements. We show that it is possible to do this in a way that guarantees that $|\trace(E_i \omega_t) - \trace(E_i\rho)|$, the error in our prediction for the next measurement, is at least $eps$ at most $O(n / eps^2) $\ times. Even in the non-realizable setting---where there could be arbitrary noise in the measurement outcomes---we show how to output hypothesis states that incur at most $O(\sqrt {Tn}) $ excess loss over the best possible state on the first $T$ measurements. These results generalize a 2007 theorem by Aaronson on the PAC-learnability of quantum states, to the online and regret-minimization settings. We give three different ways to prove our results---using convex optimization, quantum postselection, and sequential fat-shattering dimension---which have different advantages in terms of parameters and portability.

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